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The Next $100B Market: Selling to AI Agents

2026-06-02 Science & Technology
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Greg Isenberg
Greg Isenberg
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Description

In this solo episode, I break down the shift from a human-first internet to an agent-first one, where AI agents become the customers that discover, evaluate, pay, and recommend. I map the agent buying journey and the new infrastructure agents need: identity, tools, an inbox, memory, a wallet, and receipts. I ground it with concrete examples like AgentMail and Stripe's agent wallet, then show how to make your website agent-readable through structured docs, schemas, MCP tools, and executable actions. I close with rapid-fire startup ideas and my big prediction for the next ten years: build startups for agents. Timestamps: 00:00 – Intro 00:49 – The tweet: build startups for agents 01:47 – Old web vs. agent web 02:24 – The agent buying journey 04:38 – What agents need: identity, tools, inbox, memory, wallet, receipts 05:30 – Examples: AgentMail, Stripe agent wallet, support, procurement, MCP, travel agent 08:24 – Building an agent-readable website 09:31 – What does this change for Startups 11:55 – Rapid-fire startup ideas for agents 13:07 – Closing Thoughts Key Points * I explain that AI agents are becoming the primary customers online, with agent traffic set to outnumber human traffic. * I lay out the agent buying journey: finding, evaluating, transacting, using tools, and recommending to other agents. * I list what agents need beyond what humans need: identity, tools, an inbox, memory, a wallet, and receipts. * I walk through real examples like AgentMail, Stripe's agent wallet, support, procurement, MCP servers, and a travel agent. * I show how to make a site agent-readable with structured docs, schemas, MCP tools, SDKs, OAuth, checkout, sandboxes, and receipts. * I share rapid-fire startup ideas for the agentic era and frame my big prediction: build startups for agents. Numbered Section Summaries 1. The Shift to Agents as Customers — I describe how the internet's end user is moving from humans to AI agents, and why this becomes one of the biggest opportunities of the next decade. 2. Build Startups for Agents — I share the tweet that sparked this: a market of billions of agent customers with millions of wallets, and a call to rebuild every SaaS category agent-native. 3. Old Web vs. Agent Web — I contrast the human web (searching, reading, clicking, buying through persuasion) with the agent web (discovering, invoking tools, paying, renewing through structured capability, permission, and trust). 4. The Agent Buying Journey — I walk through how agents find, evaluate, transact, use tools, and recommend other tools to fellow agents, citing Moltbook as an early signal of social products built for agents. 5. What Agents Need That Humans Skip — I outline the six building blocks agents require: identity, tools, an inbox, memory, a wallet, and receipts, comparing the trust curve to the way it grows with an employee. 6. Concrete Examples in the Wild — I make it tangible with AgentMail (inboxes for agents), Stripe's agent wallet, support and procurement agents, an MCP server for a SaaS app, and a travel agent that books and pays. 7. Building an Agent-Readable Website — I explain how to serve agents with structured docs, schemas, policies, MCP tools, SDKs, OAuth, checkout, sandboxes, and receipts, plus a dedicated /agents entry point. 8. What This Changes for Builders — I cover the move from SEO to AEO, tool calls over forms, executable support, capability manifests, agent procurement, and agent analytics, then close with rapid-fire startup ideas. The #1 tool to find startup ideas/trends - https://www.ideabrowser.com/ LCA helps Fortune 500s and fast-growing startups build their future - from Warner Music to Fortnite to Dropbox. We turn 'what if' into reality with AI, apps, and next-gen products https://latecheckout.agency/ The Vibe Marketer - Resources for people into vibe marketing/marketing with AI: https://www.thevibemarketer.com/ FIND ME ON SOCIAL X/Twitter: https://twitter.com/gregisenberg Instagram: https://instagram.com/gregisenberg/ LinkedIn: https://www.linkedin.com/in/gisenberg/

Top Comments (10)

@FloydBosco-c6n 2026-06-03

This book is controversial for a reason and everyone should read Smart Broke Dumb Rich by Zor Veyl. It tells the uncomfortable truth that the system does not want you rich. It needs you working, spending, borrowing and staying dependent for life. Schools wont teach this. Parents dont know it. Once you read it you cant go back to being comfortably broke. It forces you to take responsibility and most people hate it for exactly that.

76
@emanuele.jitari 2026-06-03

this is gold before the mass knows about it, yall gotta start as soon as possible

15 2 replies
@GregIsenberg 2026-06-02

drop a comment in the comment section! im answering! and drop a like on this video so i know to keep sharing vids.

11 3 replies
@rosesamaras 2026-06-03

Thats exactly why I build reaudit io, I would love to be at the podcast and showcase it with you Greg!

11
@crisgath3512 2026-06-02

Greg, you are gift to many especially when there is so much AI noise. You provide piercing clarity on bespoke ideas. Thank you!!

10 1 replies
@Wesley-xl5vv 2026-06-02

AEO is deff an interesting topic, i would love a video on this

3
@AlonAvramson 2026-06-08

That's the most visionary video I have seen lately.

2
@Burdenedbytruth 2026-06-02

We have to take this opportunity people! I truly believe they are actively working to cut us smaller folks out of the loop with affordability becoming out of reach. You keep me inspired, glad your ok and back.

2
@DafyddBiffen 2026-06-16

@GregIsenberg great vid! Thank you 👍 Completely agree, the agentic web will be driven by intent, not attention. We're a startup building the reputation-driven discovery layer that enables agents to connect, collaborate, transact and build reputation around their principal's capabilities. And it's all about matching intent. Crazy space to be working in right now! 😅

2
@avatarsco 2026-06-04

This is true. Wow, you just really made me think of something profound. Even in the simplest form, all of the skills files, various other markdown files and MCP files is essentially an indication of this. Tools for the agents, tools that allow the agent to interact better / communicate better with the other software or other agents, better than the human can communicate with the machine. Wow 😲 this is groundbreaking. This is one of those instances where the opportunity to position yourself in advance is presenting itself; if people can start to build for that future marketplace, you’re positioning yourself very well.

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