The Pat McAfee Show Picks & Predicts Every Game For NFL's 2025 Week 6 Weekend
Weekly NFL Picks Analysis and Betting Insights
Gain expert opinions and analysis on every NFL matchup for the upcoming week to inform your betting strategies. Readers will see where the hosts agree and disagree on spread picks and identify potential schedule traps.
Short Summary
- Hosts overwhelmingly favored the listed favorites in the early NFL slate (6 out of 6 initial picks).
- Significant disagreement emerged on the Lions @ Chiefs matchup, where the small spread signaled a major underlying concern to the panel.
- The Bengals received unanimous underdog support (+14.5) against the Packers, relying heavily on backup QB Joe Flacco.
- The panel analyzes situational factors, including bye weeks, international travel, and noted historical coaching records across the slate.
- This analysis provides bettors with the consensus and counterpoints for all major weekly matchups.
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Top Comments (10)
I got Vikings over the Texans during the bye. I think Vikings are just more prepared for it.
" DeShawn Watson looks healthy." My Brother he has had 5000 massages. He'd better look healthy.
PMS NFL Picks Week 6 Pat Eagles (-7) Lost by 17 ❌️ Broncos (-6.5) Won by 2 ❌️ Steelers (-5.5) Won by 14 ✅️ Cowboys (-3) Lost by 3 ❌️ Chargers (-3.5) Won by 2 ❌️ Patriots (-3.5) Won by 6 ✅️ Rams (-7) Won by 14 ✅️ Jags (+1.5) Lost by 8 ❌️ Colts (-6.5) Won by 4 ❌️ Titans (+4.5) Lost by 10 ❌️ 49ers (+3.5) Lost by 11 ❌️ Bengals (+14.5) Lost by 9 ✅️ Chiefs (-2.5) Won by 13 ✅️ Falcons (+3.5) Won by 10 ✅️ Bears (+5.5) Won by 1 ✅️ Record This Week 7-8. Record Last Week 9-5. Overall Record 42-50-1. Overall Head to Head 2-3-1. AJ Giants (+7.5) Won by 17 ✅️ Broncos (-6.5) Won by 2 ❌️ Steelers (-5.5) Won by 14 ✅️ Cowboys (-3) Lost by 3 ❌️ Chargers (-3.5) Won by 2 ❌️ Patriots (-3.5) Won by 6 ✅️ Rams (-7) Won by 14 ✅️ Jags (+1.5) Lost by 8 ❌️ Colts (-6.5) Won by 4 ❌️ Raiders (-3.5) Won by 10 ✅️ Bucs (-3) Won by 11 ✅️ Bengals (+14.5) Lost by 9 ✅️ Lions (+2.5) Lost by 13 ❌️ Bills (-3.5) Lost by 10 ❌️ Commanders (-5.5) Lost by 1 ❌️ Record This Week 7-8. Record Last Week 11-3. Overall Record 46-45-2. Overall Head to Head 3-2-1.
Most pickers have said the 49ers would lose every week but somehow they 4-1 without anyone 🤯
CHARGERS vs DOLPHINS is gonna be a shootout. No RBs, no Def, no Olines, just guns all the way!
These videos always helpin with the last few hours of the work week
Connor’s bit on the Spencer Rattler was so funny😂
Thanks for staying consistent boys!! A lot of us appreciate your efforts! Remember get it while the getting is good Boys need to start making merch
The Bengals have so much salary cap space. They just need to use it
“Herbert has never beat the dolphins” talking out his ass right there lol😂😂😂
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Top Comments (10)
I got Vikings over the Texans during the bye. I think Vikings are just more prepared for it.
" DeShawn Watson looks healthy." My Brother he has had 5000 massages. He'd better look healthy.
PMS NFL Picks Week 6 Pat Eagles (-7) Lost by 17 ❌️ Broncos (-6.5) Won by 2 ❌️ Steelers (-5.5) Won by 14 ✅️ Cowboys (-3) Lost by 3 ❌️ Chargers (-3.5) Won by 2 ❌️ Patriots (-3.5) Won by 6 ✅️ Rams (-7) Won by 14 ✅️ Jags (+1.5) Lost by 8 ❌️ Colts (-6.5) Won by 4 ❌️ Titans (+4.5) Lost by 10 ❌️ 49ers (+3.5) Lost by 11 ❌️ Bengals (+14.5) Lost by 9 ✅️ Chiefs (-2.5) Won by 13 ✅️ Falcons (+3.5) Won by 10 ✅️ Bears (+5.5) Won by 1 ✅️ Record This Week 7-8. Record Last Week 9-5. Overall Record 42-50-1. Overall Head to Head 2-3-1. AJ Giants (+7.5) Won by 17 ✅️ Broncos (-6.5) Won by 2 ❌️ Steelers (-5.5) Won by 14 ✅️ Cowboys (-3) Lost by 3 ❌️ Chargers (-3.5) Won by 2 ❌️ Patriots (-3.5) Won by 6 ✅️ Rams (-7) Won by 14 ✅️ Jags (+1.5) Lost by 8 ❌️ Colts (-6.5) Won by 4 ❌️ Raiders (-3.5) Won by 10 ✅️ Bucs (-3) Won by 11 ✅️ Bengals (+14.5) Lost by 9 ✅️ Lions (+2.5) Lost by 13 ❌️ Bills (-3.5) Lost by 10 ❌️ Commanders (-5.5) Lost by 1 ❌️ Record This Week 7-8. Record Last Week 11-3. Overall Record 46-45-2. Overall Head to Head 3-2-1.
Most pickers have said the 49ers would lose every week but somehow they 4-1 without anyone 🤯
CHARGERS vs DOLPHINS is gonna be a shootout. No RBs, no Def, no Olines, just guns all the way!
These videos always helpin with the last few hours of the work week
Connor’s bit on the Spencer Rattler was so funny😂
Thanks for staying consistent boys!! A lot of us appreciate your efforts! Remember get it while the getting is good Boys need to start making merch
The Bengals have so much salary cap space. They just need to use it
“Herbert has never beat the dolphins” talking out his ass right there lol😂😂😂