So I Tried Ketamine… | Bryan Johnson Podcast
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Ketamine's Brain Impact, Drug Safety Protocols, and Longevity Potential
Investigate the actual neurological effects of ketamine using real-time brain monitoring and assess critical drug safety measures against deadly contaminants like fentanyl.
Short Summary
- Ketamine scrambles brain connectivity patterns, creating a temporary "therapeutic window" crucial for lasting behavioral change.
- Cocaine dramatically shortens lifespan, comparable to heavy smoking, offering no clear longevity benefits.
- Fentanyl contamination in street drugs makes Naloxone/Narcan essential emergency preparedness for everyone.
- One pilot study suggests ketamine infusions might reverse biological age markers, though this effect may correlate with depression relief.
- Gain clarity on the distinction between classical psychedelics (serotonin targets) and ketamine (NMDA target) regarding addictive potential.
This session dissects the risks and reported benefits of various substances, focusing heavily on emergent research regarding ketamine's effect on brain plasticity and longevity markers. We contrast this potential with the severe, proven cardiovascular risks of stimulants like cocaine and outline immediate harm reduction steps necessary due to widespread fentanyl adulteration in unregulated drugs. Utilize the data to inform decisions about novelty, health, and immediate safety preparedness.
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Top Comments (10)
Bro won't eat a nugget but will do coke and ketamine. I like this guy.
The UK youth have been pioneering this research for decades
A well known side-effect of Ketamine is you just can't shut up about going to Mars.
Cocaine protocol by bryan johnson was not on my 2025 bingo card
we will watch this as a family after dinner today
I love how you guys don't find certain topics weird. Usually if the topic at the beginning was brought up people struggle to really explore it at all. It's refreshing
Always love that Bryan leans into people poking fun at him.
"I dont't have a Protocol set up for that" - is my new favorite excuse
When I read about Bryan Johnson, I thaught He was some boring guy. When I listen to him, bro is super interesting !! I've learned a lot from him. Thank you Bryan and scew mainstream media !
I have a Ketamine prescription. 90mg troches. And I can say that It has helped me drastically. It melted my anxiety away and made it so I don't dread every single social interaction. I also started doing brain exercises on it. I completely rewired my brain and created a system where I do the sauna, workout, meditate in the sauna, stretch, study forex trading and eat the same exact healthy food in the morning. I cut out all seed oils and unhealthy carbs as well. My experience has been life changing. I would recommend recreating your habits while you have that window of plasticity.
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Top Comments (10)
Bro won't eat a nugget but will do coke and ketamine. I like this guy.
The UK youth have been pioneering this research for decades
A well known side-effect of Ketamine is you just can't shut up about going to Mars.
Cocaine protocol by bryan johnson was not on my 2025 bingo card
we will watch this as a family after dinner today
I love how you guys don't find certain topics weird. Usually if the topic at the beginning was brought up people struggle to really explore it at all. It's refreshing
Always love that Bryan leans into people poking fun at him.
"I dont't have a Protocol set up for that" - is my new favorite excuse
When I read about Bryan Johnson, I thaught He was some boring guy. When I listen to him, bro is super interesting !! I've learned a lot from him. Thank you Bryan and scew mainstream media !
I have a Ketamine prescription. 90mg troches. And I can say that It has helped me drastically. It melted my anxiety away and made it so I don't dread every single social interaction. I also started doing brain exercises on it. I completely rewired my brain and created a system where I do the sauna, workout, meditate in the sauna, stretch, study forex trading and eat the same exact healthy food in the morning. I cut out all seed oils and unhealthy carbs as well. My experience has been life changing. I would recommend recreating your habits while you have that window of plasticity.