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Berberine: Liver and Metabolic Health

2023-02-11 Entertainment
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Drbeen Medical Lectures
Drbeen Medical Lectures
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Berberine: Liver and Metabolic Health Talk #1 on Berberine: https://youtube.com/live/Gbn0ZTlgMo0 Berberine is a magical molecule with a vast array of effects. Today we will focus on the mechanism of the impact of BBR on liver and glucose levels. If you like this content and want more, I am doing a special lifetime membership offer. Click here: https://www.drbeen.com/yt-special/ Want to support this work?: Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true PayPal: https://paypal.me/mobeensyed?locale.x=en_US My substack: https://mobeensyedmd.substack.com/ #drbeen #koolbeens #Nutrition Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list from Sunday, Feb. 10 2023 Berberine is an insulin secretagogue targeting the KCNH6 potassium channel | Nature Communications https://www.nature.com/articles/s41467-021-25952-2 AMP-activated protein kinase - Wikipedia https://en.wikipedia.org/wiki/AMP-activated_protein_kinase Frontiers | Cerebral Gluconeogenesis and Diseases https://www.frontiersin.org/articles/10.3389/fphar.2016.00521/full Phosphoenolpyruvate carboxykinase - Wikipedia https://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase Gluconeogenesis - Wikipedia https://en.wikipedia.org/wiki/Gluconeogenesis Metformin - Wikipedia https://en.wikipedia.org/wiki/Metformin Sterol regulatory element-binding protein 1 - Wikipedia https://en.wikipedia.org/wiki/Sterol_regulatory_element-binding_protein_1 The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707648/ mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis | PNAS https://www.pnas.org/doi/10.1073/pnas.1000323107 Insulin Signaling Pathway | Antibodies.com https://www.antibodies.com/insulin-signaling-pathway Regulation of SREBP by insulin signaling pathway  | Download Scientific Diagram https://www.researchgate.net/figure/Regulation-of-SREBP-by-insulin-signaling-pathway_fig3_258503248 The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976015/ Frontiers | Glucose-lowering effect of berberine on type 2 diabetes: A systematic review and meta-analysis https://www.frontiersin.org/articles/10.3389/fphar.2022.1015045/full ATP-sensitive K+ channels in pancreatic beta-cells. Spare-channel hypothesis - PubMed https://pubmed.ncbi.nlm.nih.gov/2452107/

Top Comments (10)

@onlyhis5870 2023-02-16

You’re constant admonition to ‘consult your doctor’ doesn’t hold the same weight as it did prior to CVD. Now we’re wide awake to what we’re dealing with, and that the vast majority of ‘doctors’ are essentially paid hitmen! Thank you for sharing and explaining this to us. It is greatly appreciated!

61 2 replies
@johnsnider2006 2023-02-11

Most physicians would not know what berberine does let alone the drug interactions... Basically you are on your own in the US if you are taking it.

58 14 replies
@MandaPandaaaah 2023-02-12

I have been taking Berberine for 6 months and it has been a miracle for me. I am taking it for weightloss. The weight has literally been melting off after taking this. It helps me by working as an appetite suppressant, this helps me maintain a caloric deficit. It also gives me energy. I take 1000 MG. I started with 500 MG and it did not work as well. I have not had any side effects. I absolutely love this vitamin. I suggest mixing it with a keto or low carb zero sugar diet. That is if you seek to use this for weight loss.

51 12 replies
@Cybernurse2020 2023-02-11

I've been taking Berberine for several years (for all properties Dr. Been discussed). It's also popular among the "anti-aging biohackers", along with Metformin and Rapamycin.

28 3 replies
@uncommonsense5876 2023-06-19

As a 50-something with near type 2 diabetes, Berberine has made miraculous impact in just 4 weeks of taking daily. This little natural molecule is God send 🙏😊❤

20
@areugnat5484 2023-02-11

I’ve been taking berberine for about 6 months and was very happy to learn the details of the mechanism of action. Thank you!

18 5 replies
@9111logic 2023-02-12

🇬🇧🙏This is simply magnificent! How many pathways and mechanisms ! Love it ! Thank you Dr. Mobeen 🥰🙏🙏🙏

7
@BCSTS 2023-02-11

It would be nice if doctors even knew what berberine is!

4
@אליאלבן-דן 2023-02-11

Thank you for all this wonderful information.

4
@lozgod 2026-04-27

Discussing Berberine with my doctor. “Hey doctor I want to try Berberine”. Doctor: “what’s Berberine?” 😂

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