Bizarre Structures Inside Blood May Be Responsible for Long COVID

A protein infamous for forming fibrils when it misfolds, aggregating with the remnants of mitochondrial membranes, is alpha-synuclein. Though it is most often referred to in the context of Parkinson's, it is in fact also a precursor to neuronal inclusions in Alzheimer’s (NACP) and overexpressed in the skin of people with melanoma, to give some examples. Research has shown COVID can trigger the misfolding of this protein, increasing the risk of the associated health issues. If you'd like to check out the science: I discuss a few key scientific references in an article relating post-viral syndromes like Post-Covid to mitochondria and alpha-synuclein. I added it to my channel, as "A call for cooperation on health". The more you look into the science of damaged mitochondria, due to oxidative stress, cardiolipin peroxidation and aggregation of misfolding proteins, the more it may become clear to you that concerning chronic or degenerate conditions, much of it is a synucleinopathy, i.e. a mitochondrial or metabolic issue.

I've had chronic fatigue syndrome for 32 years, from back when medical people were sarcastically calling it "yuppie flu". I wasn't a yuppie, I was a 17 yr old who'd been hospitalized with mono (Epstein Barr Virus) because it was so bad they thought my spleen might need to come out. It was swollen to the rupture point. Nurses wrapped me in foam padding, and I had to ring for help if I wanted to roll over. I slept as much as 20 hrs a day for 4 weeks. They said they'd never seen someone hit so hard by EBV. I was so weak that I needed 2 years of physical/vocational rehab to drive a car and stay upright in the daytime. Still, nobody believed me that I felt so exhausted, it was as if the infection had never truly gone. Doctors called it neurotic, dependent needs for affection and attention when I kept coming to them for answers about the pervasive lethargy and relapsing symptoms (the thing I couldn't understand their dismissive attitude about most) like my constantly swelling/shrinking spleen. My family called me a na'er-do-well, my husband called me a drama addicted burden, doctors called me a neurotic liar. But here came long COVID, and there's so many people suffering various degrees of debilitation, from persistent crushing fatigue with vague symptoms that come and go, to full on relapses of the acute illness, that we can't all be liars, so here we are, researching and finding things like little foreign structures in blood. I'm pushing 50 now and it hardly matters to me. I pace myself as a homemaker and do what I can do each day. My kids are grown. The times when I had dreams for a career and a life full of pursuits are gone. I hardly care what happens, except I'm very happy the younger people, like PhysicsGirl, might have a chance at a real life. They don't deserve this. None of us do. The medical establishment can kiss my a$$. If they'd lifted a finger for people like me when we were begging for help, the virology might have been in place to prevent anyone from suffering so much from COVID.

From a medical professional standpoint, the multitude of widely different symptoms absolutely screams that it's a vascular problem, which could readily effect multiple organs and systems throughout the body, and with a wide variety of presentations. So microclots and possibly associated vasculitis are very strong contenders for the main cause of long COVID.

This hits hard...Ive never been the same since 2021,when I had my first infection with delta variant. Brain fog and cognitive problems being the main incapacitation. It was hell. Every test came back normal, I didnt know what was going on and the impact it had on me was awful. I was 18 back then...Thank you so much Anton for bringing light to this topic!!

Thanks Anton! Getting reliable information without the usual hype is so important when it comes to situations like this. You're doing very valuable work!

I have had a pretty serious/long lasting experience of long covid since 2022, consisting of pain on exertion and lasting 3 days if I did too much, so it was very debilitating to my life. I spent the last 3 years researching, trying to find an answer for myself and I kept coming up on possible intersections which might be served by GLP-1s. As I had weight to lose anyways, I decided to ask my doctor for it, and I am convinced it is beginning to heal me, so I would be interested in hearing your take on that. One thing which gave me a lot of hope early on was that in a blood test done before I started the GLP-1 my blood was disturbingly thick and slow to come out. And in a blood test done shortly after, it was already much more normal in appearance. I couldn't see anything in the lab results which would explain why. The science is only suggestive, but there was enough there about GLP-1s and improvement in endothelial health and issues with fibrins that I went for it and so glad that I did.

Your channel doesn't get enough praise, thank you

The Elephant in the Room!

Medical term: Bombaclot Covid

Good that you cover this. Thank you!❤