Redesigning The Molecules of Life | Brian Greene & David Baker

Nobel laureate David Baker joins Brian Greene to discuss groundbreaking work that leverages the chemistry of life to design powerful new molecules with wide ranging applications. Moderator: Brian Greene Guest: David Baker 00:00:07 - Introduction: David Baker and Protein Design 00:01:28 - How David Baker Shifted from Philosophy to Biology 00:04:58 - What Are Proteins and How Do They Function? 00:08:26 - How Many Proteins Exist and Have Been Studied? 00:11:33 - Why Protein Folding Is Crucial to Function 00:13:10 - How Scientists Predict Protein Structure 00:18:36- DeepMind's AlphaFold Breakthrough 00:25:25 - From Prediction to Design: Custom Proteins 00:27:53 - Making Proteins in the Lab: The Process 00:31:06 - Real-World Uses: Influenza & Snake Venom Blockers 00:33:04 - Generative AI for Protein Design 00:35:47 - Building Catalysts to Break Down Plastics & Methane 00:40:42 - Applications in Pharma and Disease 00:45:47 - Making Plants More Climate Resilient 00:51:38 - Future of Protein-Based Machines 00:54:20 - Neurodegenerative Disease Research 00:59:23 - Brain-Computer Interfaces and Sensors 01:01:48 - Adapting to Deep Learning: A Scientist’s Mindset 01:06:17 - Where AI and Physics Methods Intersect VISIT our Website: http://www.worldsciencefestival.com FOLLOW us on Social Media: Facebook: / worldsciencefestival Twitter: / worldscifest Instagram: / worldscifest TikTok: / worldscifest LinkedIn: / world-science-festival #worldsciencefestival #briangreene #biology