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This Molecule Targets the ROOT Cause of Gray Hair

2025-03-09 Science & Technology
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Modern Healthspan
Modern Healthspan
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Here we look at how luteolin helps to preserve the natural hair colour by slowing down senescence of keratinocytes in the hair follicle. Some links are affiliate links so we will earn a commission when they are used to purchase products. If you would like to support our channel please consider joining our patreon https://patreon.com/ModernHealthspan Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) n1o1 Nitric Oxide 10% discount with code Modern https://tinyurl.com/3esakm4s n1o1 Nitric Oxide Lozenges https://tinyurl.com/yh4rrtht Age-Defiance Face Cream https://tinyurl.com/4zr959zh DoNotAge 10% discount code MHS https://tinyurl.com/6dbvhv87 Creatine http://tinyurl.com/m6jc9auf CoQ10 https://tinyurl.com/4tpjxw7r Renue By Science 10% discount code MHS: https://tinyurl.com/37ahmr7d Skin & Body Essentials https://tinyurl.com/536zvrcr Wellness Extract 10% discount Code MODERNWE Geranylgeraniol Essential http://wellnessextract.com/RICHARDWE Delta Gold Vit E ProHealth 15% discount code: MODERN NMNH 125mg https://prohealth.pxf.io/kOaR53 Pendulum 20% Discount Code HEALTHSPAN Akkermansia pendulumtherapeutics.sjv.io/baoQVg Metabolic Daily https://pendulumtherapeutics.sjv.io/NkqE0q OmegaQuant 5% discount Code MODERN https://omegaquant.com/shop/ Bulletproof 15% off with coupon code: HEALTHSPAN15: https://tinyurl.com/4npjk5vp Inner Fuel Gut support https://bulletproof.fdf2.net/PyDKDM Omega-3 Krill Oil https://bulletproof.fdf2.net/xkdxmy Nuchido Time+ 20% discount of first purchase with code MODERN20 https://nuchido.com/MODERN OneSkin 15% Discount: Code MODERN https://tinyurl.com/3t6tevj8 OS-01 Face Topical Supplement https://tinyurl.com/29c8wrr2 NOVOS Core $5 discount CODE 5OFFMHS24 https://novos.sjv.io/daqJ0Q ☕If you would like to support our channel, we’d love a coffee…thank you! https://www.buymeacoffee.com/mhealthspan 🌐Links in this video Anti-Graying Effects of External and Internal Treatments with Luteolin on Hair in Model Mice https://www.mdpi.com/2076-3921/13/12/1549 The Protective Properties of Luteolin: A Comprehensive Review https://www.researchgate.net/publication/380519151_The_Protective_Properties_of_Luteolin_A_Comprehensive_Review *************************************** Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation. Audio Copyright Disclaimer Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to [email protected]. ********************************************** #grayhair #haircare #luteolin

Top Comments (10)

@peterz53 2025-03-09

Luteolin may also affect expression of some of the Yamanaka Factors. Found one study which indicated Luteolin increased expression of SOX2. In fact apigenin and luteolin may both increase expression of some of the YFs (SOX2 and KLF4). Valter Long mentioned one time that the FMD increased expression of some YFs, and the literature bears that out with regard to OCT4 and maybe SOX2. Use of natural compounds during short fasting periods (3 or 4 day FMD) may be a way to periodically upregulate YFs thereby supporting tissue regeneration, and killing off of excess senescent cells depending on the cocktail. Kind of surprised that this simple approach isn't being tested.

56 10 replies
@anthonyseddon1666 2025-03-09

luteolin also raises nad+ by inhibiting cd38

32 5 replies
@darkhorseman8263 2025-03-10

We knew about this 8 years ago. Why they discovered it and then dropped the research for almost a decade is beyond me.

20 3 replies
@theBigEastBand 2025-03-09

Parsley too

19
@scottmiller2591 2025-03-11

I must admit luteolin flew under my radar. I don't care very much about my hair greying, although I did note that NAC seemed to darken my grey hair - it was noticeable enough that others commented on it, and I saved some strands where there was a clear line of demarcation in color. I dug into luteolin a little, and was surprised to see the range of effects you noted here, with support of brown fat being yet another effect. Artichoke extract (which I take) has luteolin in it, but again, the concentration is low - some 200 mg/kg of extract, clearly not a practicable source. I have to caution against too much antioxidant - you need stress markers to get muscle growth from exercise.

13
@KasKade7 2025-03-09

No mention of radicchio. One of the best sources of luteolin.

11
@ModernHealthspan 2025-03-09

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4 1 replies
@erwinrogers9470 2025-03-10

Great information👍

2
@EyepowerRedREDLIGHTGLASSES 2025-03-10

thank you so much Richard, excellent lecture and video

1
@erwinrogers9470 2025-03-10

Love it🔥

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