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3 Interventions to Show Aging is Treatable: The US Government’s $38M Bet

2026-04-16 Science & Technology
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Modern Healthspan
Modern Healthspan
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The US Government is finally treating aging as a modifiable condition. Discover the VITAL-H trial: a $38M federal study testing Rapamycin, Semaglutide, and Dapagliflozin to set the first FDA-approved roadmap for healthy longevity. Some links are affiliate links so we will earn a commission when they are used to purchase products. If you would like to support our channel please consider joining our Patreon https://patreon.com/ModernHealthspan ~~~~~~~~~~~~~~ *Qualia* (15% off: MODERN) Creatine+ https://tinyurl.com/mr3z35jd Senolytic https://bit.ly/4jlaibe *Renue By Science* (10% off: MHS) https://tinyurl.com/bdew4bfs NMN Powder • Lipo NR *BiOptimizers* (15% off: MHBIO) https://bit.ly/47VAa8f - Magnesium Breakthrough, Gluten Guardian *Seeking Health* (10% off: Richard10) https://crrnt.app/SEEK/-dm0MyrQ, Histamine Nutrients https://crrnt.app/SEEK/EpM7paAO *Stemregen* (15% off: MODERN) *US only* https://tinyurl.com/45z968yr *MitoQ* https://tinyurl.com/5n93fm3f MitoQ Pure https://tinyurl.com/3hxy9s7x *Wellness Extract* (10% off: MODERNWE) http://wellnessextract.com/RICHARDWE Geranylgeraniol • Vit E *n1o1* (10% off: Modern) https://tidd.ly/3IczGRW - Nitric Oxide Lozenges *AX3 Life* (20% off: MODERN20) https://tinyurl.com/2t3w26nw - Astaxanthin *Qitone* (10% off: HEALTH10) https://tidd.ly/4jGklry Qitone Esters Powder *Oxford Healthspan* (15% off: MHS) https://tinyurl.com/hrxfnzpn - Spermidine *ProHealth* (15% off: MODERN) https://prohealth.pxf.io/aObQRR NMNH 500mg These are affiliate links - using them supports the channel at no extra cost to you. ~~~~~~~~~~~~~~ Is aging finally becoming a recognized medical priority? In this video, we break down the historic VITAL-H trial, a $38 million initiative funded by ARPA-H (the "DARPA of health"). This isn't just another study; it is a nationwide clinical effort to validate a new regulatory framework for healthspan. We dive deep into the "Big Three" interventions: Rapamycin for cellular autophagy, Dapagliflozin for metabolic and cardio-renal protection, and Semaglutide for steady-state metabolic resilience. Unlike previous trials, VITAL-H uses a decentralized model with wearables like the Oura Ring and Whoop to track "Intrinsic Capacity"; a World Health Organization framework covering mobility, cognition, and vitality. Most importantly, we discuss the "regulatory plumbing." By working directly with the FDA to establish quantifiable goalposts like gait speed and grip strength, VITAL-H could provide the first-ever "fast-track template" for future longevity therapies. Learn about the timeline, the low-dose oral protocols, and why this represents a definitive shift in national health policy. 📚 Chapters 0:00 The $38M Shift: Government-Funded Longevity 1:33 Measuring "Intrinsic Capacity" vs. Lifespan 2:41 The Protocol: Rapamycin, Semaglutide & Dapagliflozin 3:54 Technical Deep Dive: Mechanisms of Action 6:28 The Decentralized Model: Wearables & Real-Time Data 7:20 The FDA Bottleneck: Creating a Regulatory Template 8:19 Which Intervention is Most Critical? (Community Question) 🌐Links in this video News on the trial https://news.uthscsa.edu/barshop-institute-to-receive-up-to-38-million-from-arpa-h-anchoring-ut-san-antonio-as-a-national-leader-in-aging-and-healthy-longevity-science/ https://news.uthscsa.edu/ut-san-antonio-to-lead-38-million-national-trial-testing-drugs-to-extend-healthspan/ ARPA-H Website https://arpa-h.gov/ PROSPR Website https://arpa-h.gov/explore-funding/programs/prospr *************************************** Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation. Audio Copyright Disclaimer Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to [email protected]. ********************************************** #longevity #VITALH #Healthspan

Top Comments (7)

@Enhancedgenetics 2026-04-17

GHK CU 💪📈😀

1 2 replies
@DoctorHemi 2026-04-16

Looking forward to the results!

1 1 replies
@farshidmoghaddam8504 2026-04-16

Hi. All three 😊

1 1 replies
@patrickmchargue7122 2026-04-17

Boomers are finally finding their voice. They are pushing legislators and drug companies to do the research and development that will help us all. Oh - and rapamycin is my pick for the best evidence-based treatment.

1 1 replies
@ModernHealthspan 2026-04-16

If you would like to support our channel please consider joining our Patreon https://patreon.com/ModernHealthspan *Qualia* (15% off: MODERN) Creatine+ https://tinyurl.com/mr3z35jd Senolytic https://bit.ly/4jlaibe *Renue By Science* (10% off: MHS) https://tinyurl.com/bdew4bfs NMN Powder • Lipo NR *BiOptimizers* (15% off: MHBIO) https://bit.ly/47VAa8f - Magnesium Breakthrough, Gluten Guardian *Seeking Health* (10% off: Richard10) https://crrnt.app/SEEK/-dm0MyrQ, Histamine Nutrients https://crrnt.app/SEEK/EpM7paAO *Stemregen* (15% off: MODERN) *US only* https://tinyurl.com/45z968yr *MitoQ* https://tinyurl.com/5n93fm3f MitoQ Pure https://tinyurl.com/3hxy9s7x *Wellness Extract* (10% off: MODERNWE) http://wellnessextract.com/RICHARDWE Geranylgeraniol • Vit E *n1o1* (10% off: Modern) https://tidd.ly/3IczGRW - Nitric Oxide Lozenges *AX3 Life* (20% off: MODERN20) https://tinyurl.com/2t3w26nw - Astaxanthin *Qitone* (10% off: HEALTH10) https://tidd.ly/4jGklry Qitone Esters Powder *Oxford Healthspan* (15% off: MHS) https://tinyurl.com/hrxfnzpn - Spermidine *ProHealth* (15% off: MODERN) https://prohealth.pxf.io/aObQRR NMNH 500mg These are affiliate links - using them supports the channel at no extra cost to you.

1
@thomascorbett2936 2026-04-26

Id like all 3 in one pill in the proper proportion .

0 1 replies
@summerforever6736 2026-04-17

TOTAL NONSENSE!! THE US GOV WANTS YOU TO DIE NOT LIVE LONGER!! ASK BILL GATES???

0 1 replies

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