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Shocking Discovery That Single Cells and Even Molecules Can Learn and Exhibit Memory

2026-03-23 Science & Technology
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Anton Petrov
Anton Petrov
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Support this channel on Patreon to help me make this a full time job: https://www.patreon.com/whatdamath (Unreleased videos, extra footage, DMs, no ads) Alternatively, PayPal donations can be sent here: http://paypal.me/whatdamath Get a Wonderful Person Tee: https://teespring.com/stores/whatdamath More cool designs are on Amazon: https://amzn.to/3QFIrFX Hello and welcome! My name is Anton and in this video, we will talk about incredible discoveries about learning Links: https://www.biorxiv.org/content/10.64898/2026.02.25.708045v1.full.pdf https://www.cell.com/action/showPdf?pii=S0960-9822%2824%2901523-9 https://www.biorxiv.org/content/10.1101/2025.09.10.675114v1.full.pdf https://www.nature.com/articles/s42003-025-08411-2 Other videos: https://www.youtube.com/watch?v=spZwZLkMsYw https://www.youtube.com/watch?v=BcVQ_eH7M50 #learning #memory #biology 0:00 The idea of learning is very surprising 1:20 Associative and non-associative learning 2:35 Single cells learn without a brain 5:50 Molecular learning? Genetic Networks 7:30 Implications for the medical field 9:10 Conclusions Enjoy and please subscribe Bitcoin/Ethereum to spare? Donate them here to help this channel grow! bc1qnkl3nk0zt7w0xzrgur9pnkcduj7a3xxllcn7d4 or ETH: 0x60f088B10b03115405d313f964BeA93eF0Bd3DbF The hardware used to record these videos: New Camera: https://amzn.to/4pCVINS CPU: https://amzn.to/4qXIaxC Video Card: https://amzn.to/2M1W26C Motherboard: https://amzn.to/2JYGiQQ RAM: https://amzn.to/2Mwy2t4 PSU: https://amzn.to/2LZcrIH Case: https://amzn.to/2MwJZz4 Microphone: https://amzn.to/2t5jTv0 Mixer: https://amzn.to/2JOL0oF Recording and Editing: https://amzn.to/2LX6uvU Some of the above are affiliate links, meaning I would get a (very small) percentage of the price paid. Thank you to all Patreon supporters of this channel Special thanks also goes to all the wonderful supporters of the channel through YouTube Memberships Credit: Mark Garlick www.markgarlick.com Tim Tim CC BY SA 4.0 https://en.wikipedia.org/wiki/Slime_mold#/media/File:Physarum_polycephalum_strain_LU352_-_4.jpg Flupke59 CC BY SA 3.0 https://en.wikipedia.org/wiki/Stentor_coeruleus#/media/File:Stentor_coeruleus_extended.jpg Licenses used: https://creativecommons.org/licenses/by/4.0/ and relevant Creative Commons licenses

Top Comments (10)

@ArnoNymus 2026-03-23

I can confirm. I can sometimes learn, too.

429 18 replies
@Zora72954 2026-03-24

if you think about it, life would have never lasted as long as it has if single celled organisms couldnt learn

336 54 replies
@Moyano__ 2026-03-23

We are going on an adventure

275 37 replies
@cap-6 2026-03-24

Michael Levin out of Tufts University has many lectures and interviews on this topic and presents his research on his discoveries on this topic, which is definitely a paradigm shift for science. His research includes teaching cancer cells in animals to rejoin the collective of other non cancer cells through behavior type modification and taking seemingly non-related cells to get them to build other body parts etc. Probably the most amazing science stuff I've come across that has some potentially staggering implications. What's amazing is not the apparent behavior and getting them to do tricks, it's the apparent "mind" that they exhibit, such as with the pavlovian conditioning mentioned here. Levin talks cells ability to forgo immediate rewards for later higher rewards and many other things we associate with a human mind or behavior.

231 23 replies
@Nex_Addo 2026-03-25

Anton is low-key one of if not the most prolific and high-quality science communicator around. Very very few channels where so many of the videos are genuinely extremely interesting and recent discoveries, while also being incredibly varied in topic, and absurdly consistent in the upload schedule.

216 16 replies
@icuranme2018 2026-03-23

Learning using calcium channels in very small organisms was discussed in detail in Determined by Sapolski. Not single cell or molecules, but not complex organisms and no brain.

29
@sacha75019 2026-03-23

This channel is amazing

25
@garret1930 2026-03-24

From the moment I saw the title I thought this would be related to Michael Levin's work and lo and behold it is

23
@soroosh82 2026-03-23

Hi Anton, Since you mentioned opioids and how we don't understand the tolerance reversal part. Look up Ibogaine. If your heart is healthy, Ibogaine can reset your brain's receptors and in a 36 hour period it can completely remove all withdrawal symptoms and tolerance. Something to do with the NMDA system (I think). Love to see a video on that!

20
@earthknight60 2026-03-24

It's worth noting that we have had evidence of associative learning in plants for a while now, and that associative learning in single celled organisms has been proposed and studied before also. And in the late '70s single celled organisms were successfully trained via classical conditioning. Gagliano, et al 2016 Learning by Association in Plants (note that there is an older study from around 2003 or so showing similar findings, but I'm not finding it now) Fernando, et al 2008 Molecular circuits for associative learning in single-celled organisms Gandhi, et al 2007 Associative learning in biochemical networks Hennessey 1979 Classical conditioning in paramecia

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