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Essentials: Science of Mindsets for Health & Performance | Dr. Alia Crum

2025-09-04 Science & Technology
196.7k
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Andrew Huberman
Andrew Huberman
7.5m subscribers

The Power of Mindsets: Shaping Physiology Through Beliefs

Discover how your core beliefs about stress, food, and exercise fundamentally alter measurable physiological responses and performance. Learn actionable techniques to leverage adversity for growth rather than succumbing to perceived threats.

Short Summary

  • Mindsets (core beliefs) dictate expectations, explanations, and goals, directly influencing motivation and measurable physiology.
  • Believing a food is indulgent, even if objectively identical to a "healthy" shake, significantly changes satiety hormone (ghrelin) response.
  • Adopting a "stress is enhancing" mindset improves performance and reduces negative physical symptoms like tension and insomnia during adversity.
  • This orientation transforms the experience of stress from a debilitating event into a tool for cognitive and physical adaptation.
  • This episode provides Dr. Alia Crum’s three-step protocol for cultivating a stress-enhancing mindset.

This discussion explores concrete evidence demonstrating that reframing major life variables—like diet quality or perceived physical exertion—produces documented physical changes, moving beyond classic placebo effects to reshape bodily readiness and response. These findings offer powerful insights for optimizing health and performance by consciously managing our default assumptions.

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Description

In this Huberman Lab Essentials episode, my guest is Dr. Alia Crum, PhD, professor of psychology at Stanford University and the director of the Stanford Mind & Body Lab. Dr. Crum explains that our mindsets—for example, what we believe about stress, exercise and the food we eat—shape how we feel, behave and even how our bodies respond. We discuss studies showing simply believing a food is indulgent can shift satiety hormones and that viewing your daily activity as real exercise can improve weight loss and health markers. We also discuss how to reframe stress so it becomes a tool for growth and improved performance. Episode show notes: https://go.hubermanlab.com/rTtaOnp Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/dFR_wFN23ZY Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S *Follow Huberman Lab* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Timestamps* 00:00:00 Alia Crum 00:00:20 Mindset, Core Beliefs; Examples of Mindset 00:04:56 Mindset Shapes Body’s Response, Placebo Effects, Tool: Mindset for Weight Loss 00:10:18 Different Diets & Mindset 00:11:51 Nocebo Effect 00:12:45 Exercise Mindsets, Weight Loss & Health Benefits 00:15:31 Stress, Tool: Stress is Enhancing Mindset, Mental & Physical Benefits 00:22:43 Mindset, Stress, Motivation & Physiology; Hormones 00:26:09 Mindsets as Portals to Unconscious, Tool: Stress Mindset Awareness 00:27:43 Leverage Stress, Tool: Adopt a Stress is Enhancing Mindset 00:30:47 Mindsets Matter, Athletics 00:32:35 Resources, Toolkits & Acknowledgements Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

Top Comments (10)

@TheMindLab247 2025-09-04

Dr. Crum really shows how the mind is the body’s hidden gym. Change the way you think about stress, food, or even fatigue, and suddenly your biology follows suit. Makes you wonder, maybe the placebo effect isn’t ‘fake medicine,’ it’s just untapped potential. Imagine if we trained our mindset the way we train our muscles.

221 5 replies
@AnaHej-f9f 2025-09-04

Yes, mindset is crucial, but how can anyone keep a healthy one in today’s world? We’re fed chaos daily: endless screens, fake online ideals, financial pressure, collapsing family values. It’s not coincidence it’s design. An anxious, depressed society is easier to control and endlessly profitable. I lived that reality: constant panic, no clarity, anger at myself for not “keeping up.” The truth hit me when I stumbled upon a passage in Your Mind Was A Target by dr Voss. It reframed everything showing how these mental health crises aren’t accidental but engineered, and that we still have the power to resist by regaining control of our emotions. That small shift in perspective became the start of my recovery.

193 7 replies
@twophlaggargleblap 2025-09-04

I'm a 450 pound smoker who recently decided to get his shit together. Quit smoking, slow carb diet, lots of exercise, training focus to deal with the ADHD. Mindfulness and meditation a big thing. Taking a Goggins approach, trying to build the anterior midcingulate cortex, and Crum's 'stress is enhancing' mindset is helping with the cold showers especially. I'm not there yet but I'll get there. Thanks Dr. Huberman from a long-time wallflower listener.

117 10 replies
@hubermanlab 2025-09-04

Thank you for watching! If you enjoyed this topic and episode, please click the “Like” button and subscribe to our channel on YouTube. Thank you for your interest in science! — Andrew

108 12 replies
@ayatakinci 2025-09-04

I started watching the Huberman lab essential playlist and MY GOD how my life my mindset shifted since, thank you very much ❤️ your knowledge makes life easier to live

39
@ninahninah-f2k 2025-09-29

“Whether you think you can or you can’t, you’re right “ today’s topic reminded me of this quote

35
@SkinMkndf 2025-09-04

There is so much value in this topic. This is something to expand on. We spend so much time magnifying anxiety and stress and very little on the power of the mindsets. There needs to be more outlets relying this type of information.

15
@dvcallen6872 2025-12-20

Thank you for not polluting our brains with ads in this video, we really appreciate that and are thankful! 🙏

2
@firouzehkaramlou3746 2026-01-04

Thank you, Dr. Huberman, for the clarity and depth you consistently bring to these conversations, and thank you, Dr. Crum, for articulating so clearly how mindsets shape biology and behavior. This episode deeply resonated with my own lived experience of long-term neuroplastic change through awareness and learning. I’m especially inspired by the potential to apply these science-backed insights in education from an early age, and I would love to explore ways lived experience might meaningfully contribute to this work.

2
@MarkoCeki 2025-10-27

The idea that mindset can biologically shape our stress response is wild when you really think about it. Dr. Crum’s research shows it’s not about “positive thinking”, it’s about perception literally shifting physiology. If belief alone can enhance the body’s recovery, energy, and immune response… imagine what happens when we train mindset with the same consistency we train muscles 💪

2

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