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How to Lose Fat & Gain Muscle With Nutrition | Alan Aragon

2025-07-07 Science & Technology
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Andrew Huberman
Andrew Huberman
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Description

My guest is Alan Aragon, a renowned nutrition and fitness expert and researcher known for sharing the strongest evidence-based approaches to fat loss, muscle gain and overall health and fitness. We discuss how to optimize your protein intake, including how much to consume per meal and when, and the facts and myths about the “30-gram rule” and the “anabolic window” following exercise. We also discuss controversial topics such as seed oils, artificial sweeteners, animal vs. plant proteins, training fasted for fat loss and collagen supplementation. Alan Aragon clarifies the most important topics in nutrition and offers valuable time-saving yet extra-effective ways to exercise. He is a true expert in providing data-supported actionable exercise and nutrition protocols for anyone seeking to improve their body composition and health. Episode show notes: https://go.hubermanlab.com/FfBJCje *Thank you to our sponsors* AG1: ⁠https://drinkag1.com/huberman Carbon: ⁠https://joincarbon.com/huberman Wealthfront**: ⁠https://wealthfront.com/huberman David: ⁠https://davidprotein.com/huberman Function: ⁠https://functionhealth.com/huberman **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. *Follow Huberman Lab* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Alan Aragon* Website: https://alanaragon.com Monthly Research Review: https://alanaragon.com/aarr/#aarr-pricing-table Flexible Dieting (new book): https://amzn.to/3TVwNHM Books: https://amzn.to/461Lm49 X: https://x.com/TheAlanAragon Instagram: https://www.instagram.com/thealanaragon Threads: https://www.threads.com/@thealanaragon TikTok: https://www.tiktok.com/@thealanaragon Facebook: https://www.facebook.com/alan.aragon.796/ LinkedIn: https://www.linkedin.com/in/alan-aragon *Timestamps* 00:00:00 Alan Aragon 00:02:17 Dietary Protein & Protein Synthesis Limits?, Tool: Post-Resistance Training & Protein Intake (30-50g) 00:09:16 Training Fasted, Post-Exercise Anabolic Window, Tool: Total Daily Protein 00:15:53 Daily Protein Intake, Timing & Exercise, Muscle Strength/Size 00:23:00 Sponsors: Carbon & Wealthfront 00:26:46 Does Fasted Training Increase Body Fat Loss?, Cardio, Individual Flexibility 00:36:53 Dietary Protein & Body Composition 00:38:58 Animal vs Plant Proteins (Whey, Soy, Pea, Quorn), Muscle Size & Strength 00:51:24 Sponsors: AG1 & David 00:54:14 Body Re-Composition, Gain Muscle While Losing Fat?, Tool: Protein Intake & Exercise 01:02:55 Fiber; Starchy Carbohydrates & Fat Loss, Ketogenic Diet 01:10:36 Inflammation, Fat & Macronutrients, Hyper-Palatability; Fish Oil Supplementation 01:16:52 Added Dietary Sugars, Sugar Cravings, Tool: Protein Intake 01:24:03 Artificial Sweeteners (Aspartame, Sucralose, Saccharine, Stevia), Diet Soda, Weight Loss 01:30:16 Sponsor: Function 01:32:04 Caffeine, Exercise & Fat Loss 01:34:53 Alcohol, Red Wine, Sleep, Lifestyle; Quitting Drinking & Stress Resilience 01:44:43 Seed Oils vs Animal Fats, Canola Oil, Olive Oil, Oil Production, Tool: Improve Diet Quality 01:55:50 Butter & Cardiovascular Risk, Saturated Fat, Mediterranean Keto Diet, Testosterone 02:00:43 Menstrual Cycle, Tool: Diet Breaks; Menopause Transition & Body Composition 02:07:04 Collagen Supplementation, Skin Appearance 02:12:44 Supplements: Multivitamins, Vitamin D3, Fish Oil, Creatine, Vitamin C 02:20:03 Resistance & Cardio Training, Tool: Cluster Sets & Super Sets 02:31:35 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

Top Comments (10)

@dawidpasternak6625 2025-07-09

Aim for ~ 0.7–1 g protein per lb body-weight (1.6–2.2 g kg⁻¹). How you split it up matters far less than hitting the daily total. Roughly 25–50 g per meal (depending on body size) maximises muscle-protein synthesis; more isn’t harmful but shows diminishing returns. If you ate within ~3 h before training and hit your daily protein, rushing to chug a shake afterwards adds no measurable benefit. Even in a slight calorie surplus, pushing protein up to ~1–1.5 g lb⁻¹ often adds lean mass while dropping or maintaining body-fat. Fasted workouts burn more fat during the session, but total 24-h fat loss is identical when calories and protein are matched. Lift 3–5 days a week, using progressive overload. Supersets, cluster sets or short-rest circuits can provide a cardio hit if you’re time-strapped. Once protein and calories are set, choose the mix of whole-food carbs, healthy fats (olive oil, nuts, even canola) and plenty of fiber that you’ll stick to. Supplement “short list.” Worth considering: • Creatine 5 g day • Vitamin D₃ (2–5 k IU if sun exposure is low) • Fish-oil for ≥1 g EPA/DHA • Quality multivitamin/mineral + extra magnesium • Collagen (~15 g) + vitamin C for connective tissue/skin During the PMS week, allow a “diet break” (eat at maintenance) to tame cravings; menopausal fat-gain is modest (~3–4 lb over several years) and managed with the same protein-plus-lifting approach. Adequate sleep, stress management, limiting heavy alcohol, staying generally active (steps, walks) and choosing minimally processed foods amplify every training-and-nutrition tactic above.

623 20 replies
@rib.7809 2025-07-07

Omg. An actual conversation with a nutrition and fitness expert that didn't leave me confused!!!! WHAT?!?!?! Thank you for speaking with Alan (never heard of him before). I was hesitant to even start it because I thought, well, more confusion 😫 As a 52 yr woman and stepping into the next change in my body, I'm in a student phase in learning how to navigate it. Lots of gold, clear, science backed information was shared. I can't state enough how grateful I am for this conversation!

357 10 replies
@_kuya.e 2025-07-07

1) Maximize protein synthesis 0.2 to 0.25g per lb of bodyweight per meal 2) Protein timing before or after workout doesn't matter as long as you get 0.7g per bodyweight of protein. It all evens out at the end of the day. 3) Fasted vs unfasted cardio doesn't matter as long as calories are the same, no difference in fat loss. 4) Vegan diet vs omnivore diet. No difference in muscle size and strength in 12 weeks. As long as 0.7g per lb of bodyweight. Even if Vegan diet had significantly less BCAA's (amino acids). Shows that resistance training stimulus is a robust stimulus. Caveat is untrained participants 5) Offset inflamation of sleep deprivation with exercise **theres more, i havent finished it**

351 18 replies
@hubermanlab 2025-07-07

Thank you for watching. Please click the subscribe tab and then the "bell" icon to subscribe to our channel here on YouTube and get notified when new content is posted... And thank you for your interest in science! -- Andrew

313 20 replies
@YourIdentityIsAHoax 2025-07-07

In a world flooded with nutrition myths and fitness gimmicks, it’s refreshing to hear Alan Aragon distill evidence-based clarity. This conversation is gold for anyone tired of chasing trends and ready to focus on what actually works. Respect for bringing real science back to the table.

230 12 replies
@1purPlepeoples 2025-07-07

Really want to thank Alan for sharing his experience with quitting alcohol🙏🏼

114 8 replies
@linorodriguez9816 2025-07-08

Is anyone else just getting bombarded with YouTube ads or is it just me? I’m getting one like every few minutes and it’s painful to try to get through the whole podcast. I know it’s a free show but dayum.

98 17 replies
@inquisitive_life 2025-08-13

PLEASE get Alan and Dr Stacy Sims on the same podcast to talk about women's health!

25 1 replies
@NoirLoveManhwa 2025-12-07

Love how this video finally explains that you can lose fat and build muscle at the same time — if your nutrition is on point.

9
@danielgruic8712 2025-07-10

Alan has been one of the best speakers on nutrition since the 2000’s.

7

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