Navigate Select ESC Close

How to Build Endurance | Huberman Lab Essentials

2025-04-17 Science & Technology
357.4k
6.9k
220
Andrew Huberman
Andrew Huberman
7.5m subscribers

Unlock all features

FREE: Get instant access to 10 AI summaries, chats, or transcripts per day.

Description

In this Huberman Lab Essentials episode, I explain how to build endurance and describe targeted protocols to enhance different types of endurance. I discuss how endurance—the ability to sustain effort—requires the coordination of physical and mental systems driven by energy availability, brain willpower, and specific training adaptations in the muscles, heart, lungs and neurons. I explain conditioning protocols designed to enhance four types of endurance, from long-duration steady state to muscular endurance and high-intensity intervals, and how each training style triggers unique adaptations in the body and brain, such as improved mitochondrial function and oxygen utilization. Additionally, I highlight the crucial role of hydration and electrolytes, which are essential for neural function and influence the brain’s willpower to sustain effort. Episode show notes: https://go.hubermanlab.com/PH5df16 Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/VQLU7gpk_X8 Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S *Timestamps* 00:00:00 Huberman Lab Essentials; Build Endurance 00:00:50 Energy Sources, ATP, Oxygen 00:04:14 Neurons & Willpower, Glucose & Electrolytes 00:09:19 Heart, Lungs; Physiology & Performance Limiting Factors 00:10:35 Muscular Endurance, Protocol, Concentric Movements, Mitochondria 00:17:14 Long-Duration Endurance, Efficiency, Mitochondria, Capillaries 00:21:07 High-Intensity Interval Training (HIIT), Anaerobic Endurance, Protocol 00:27:47 High-Intensity Aerobic Endurance, Adaptations 00:30:06 Brain & Body Adaptations, Heart 00:33:57 Hydration, Tool: Galpin Equation 00:35:38 Supplements, Stimulants, Magnesium Malate 00:36:27 Recap & Key Takeaways #HubermanLab #Science #Health #Endurance Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

Top Comments (10)

@akinakinakin3 2025-04-17

In 198 days, I’ll be running 15 kilometers for the first time, across the Bosphorus in Istanbul. I’ll be crossing from one continent to another, from Asia to Europe, on foot. It’ll be my first time ever running between continents.

276 29 replies
@yadavgaming-vg5ln 2025-05-06

been in survival mode for so long i forgot what it feels like to feel well. not just functioning, but actually well. the hidden herbs reminded me that healing doesnt have to be complicated. sometimes nature already gave us what we need, we just forgot how to use it

187 3 replies
@hubermanlab 2025-04-17

Thank you for watching! If you enjoyed this topic and episode, please click the “Like” button and subscribe to our channel on YouTube. Thank you for your interest in science! — Andrew

132 5 replies
@unrealvibe98 2025-04-17

Our body is rarely the thing that gives up , it is the mind that gives up

105 4 replies
@FranklinsBenjamins 2025-04-20

These are literally changing my life. After a long time of not knowing what is wrong with me or which way to go. You’re giving people clarity on the power they possess. Thank you, Dr. Huberman

97
@Rowanj59 2025-04-17

Half the time I have no clue what you’re talking about but the times I do it’s like the biggest light bulb ever. Thank you for all the vast information you so generously provide!!!

77 3 replies
@HealthFlow8 2025-04-17

This is the kind of content that makes you rethink how you train. Endurance isn’t just physical—it’s brain chemistry, mindset, and strategy. Loved this breakdown!

65
@timothymatthews4399 2025-04-20

Dear Dr Huberman. I’m a biochemical engineer with 15 years experience at genentech until I had a massive AVM stroke in 2007 in my basal ganglia, paralyzing my dominant left side. I’ve been on a rehabilitation journey since then. I wanted to mention I’ve done a lot of independent research on hyperbaric oxygen as a means to assist recovery. This intervention has traditionally been considered “snake oil” but there’s so much data demonstrating impressive health benefits. It is approved by FDA for various conditions mainly related to wound healing. A world leader in HBOT is Dr. Paul Harch, author of ‘the oxygen revolution’. Another leader is Dr. Efrati from Tel Aviv. Harch is at LSU in Louisiana. I wonder if you’d be interested in inviting harch on your show for an episode on hyperbaric Oxygen? I LOVE your podcast and I sincerely thank you for what you’re doing.

58 2 replies
@joeyfunk4327 2025-04-17

I got one of the hardest races in the country coming up in 12 weeks, let’s Gooo!

41 9 replies
@Benbdr-y5f 2025-04-19

I usually just consume your videos- but this video helped me a lot for my major phd exams- to understand muscular endurance in a deeper MORE REASONABLE way- in German school we learn this cycle including ATP in a much more overly complicated way- so that the easy way out is just memorise it without even trying to actually understanding it--- you're a great teacher and if you ever want to be interviewed by an 18 year old high school student Hit me Up and I will ask you some major questions for teenagers, questions which evolve in my friend groups and are discussed in a longer timeframes because of all these different studies and podcast..

13

Unlock the Data Inside
Turn Videos into Knowledge

  • Get FREE 10/day: transcripts, summaries, chats
  • Chat with videos, export text & PDF
  • $1 free API credit for RAG, chatbots & research

Free forever plan • All features unlocked

App screenshot