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The 5 Most Inflammatory Foods to Ditch For Good (feel it immediately)

2025-09-24 People & Blogs
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Thomas DeLauer
Thomas DeLauer
4.0m subscribers

Identifying Top Inflammatory Foods Based on Scientific Evidence

Learn which common dietary components consistently trigger elevated inflammation markers and how paying attention to bio-individuality can protect your DNA from long-term cellular damage.

Short Summary

  • Sugary sodas disproportionately raise uric acid levels compared to diet sodas, linking sugar directly to inflammatory precursors.
  • Trans fats significantly increase key inflammatory markers, including C-reactive protein (CRP), raising cardiovascular risk markers.
  • Processed meats, not necessarily fresh red meat, correlate with higher cardiovascular disease risk due to compounds like AGEs impacting arterial flexibility. This overview highlights five problematic food categories—refined sugars, trans fats, alcohol, processed meats, and specific preservatives—grounding the advice in clinical study findings to help you modulate unnecessary chronic inflammation.

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Description

Use Code THOMAS25 for 25% off Your First Order of SEED: https://www.seed.com/thomasyt This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Click HERE to Subscribe: https://www.youtube.com/c/ThomasDeLauerOfficial?sub_confirmation=1 Please check out the new Shorts channel, DeLauer Clips and Workouts, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://pubmed.ncbi.nlm.nih.gov/26081486/ https://pubmed.ncbi.nlm.nih.gov/25905791/ https://academic.oup.com/jn/article/135/3/562/4663700 https://academic.oup.com/alcalc/article/45/2/119/135134 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885952/ https://pubmed.ncbi.nlm.nih.gov/15306213/ https://pubmed.ncbi.nlm.nih.gov/33003957/ https://pubmed.ncbi.nlm.nih.gov/24419445/ Timestamps ⏱ 0:00 - Intro 1:14 - Refined Carbs 4:04 - 25% off Your First Order of SEED 4:40 - Trans Fats 6:44 - Alcohol 8:54 - Processed Meat 11:05 - Sodium Benzoate 13:05 - Recap

Top Comments (10)

@MykoeRelic 2025-09-24

I have all but eliminated anything from my diet with sodium benzoate, wheat , grains, dairy (except yogurt, good cheese, kefir) carrageenan, corn , bread, trans fat, titanium dioxide, polysorbates, malti-dextron, MSG, high fructose corn syrup, hydrogenated oils, All sugar is gone, alcohol consumption is way down, NO processed meats/foods. I eat nothing but whole foods, all meats from Butcher Box, fish, chicken, red meats, pork. All veggies are frozen or fresh. I eat out twice a month , maybe. Have capers, sw. Potatoes or regular potatoes after 24 hrs in the fridge, long grain brown rice, the same. Took Seed for 8-9 months (can't afford it right now) I get some exercise almost every day. Omad or 2mad. I mean I'm really trying. I'm 72 and counting. I thank you Thomas for all your help and videos, I have lost 100 lbs, feel much better, but I do have some health problems that my doctors and I are addressing aggressively. Thanks so much.

38 4 replies
@political_vagrancy 2025-09-24

i had to stop drinking alcohol. My body cant handle it anymore.

34 8 replies
@MrQuadcity 2025-09-25

# Key Takeaways: The 5 Most Inflammatory Foods to Ditch For Good ## Introduction Inflammation is a natural and necessary bodily response to injury or infection. However, chronic inflammation can lead to cellular damage, DNA harm, and various health issues. Thomas DeLauer identifies five foods that consistently drive up inflammation across different individuals, though he emphasizes the concept of bio-individuality—meaning people may react differently to various foods. ## 1. Sugar and Refined Carbohydrates ### Key Points: - **Strong Evidence**: Multiple studies demonstrate that heavily refined sugars and starches trigger inflammatory responses - **Study Findings**: - 47 type 2 diabetics consuming 1 liter of sugary soda daily showed 15% increase in uric acid (a precursor to inflammation) - This effect was specific to sugar soda, not diet soda - **Mechanism**: Both glucose and fructose can drive inflammation, but fructose shows slightly more impact due to our bodies not being designed for large quantities - **Additional Effects**: High consumption leads to hyperinsulinemia, increased adipocines (inflammatory cytokines from fat cells), and fatty liver deposits - **Progression Risk**: Can lead to necroinflammation and steatohepatitis (more permanent liver issues) ### Practical Advice: Limit sugar consumption significantly, especially from processed sources. Consider alternatives like erythritol, stevia, or monk fruit. ## 2. Trans Fats ### Key Points: - **Definition**: Artificially hydrogenated fats created by adding hydrogen to unsaturated fats - **Study Evidence**: - 730 women study showed linear correlation between trans fat consumption and inflammation markers - Highest trans fat consumers had 73% higher C-reactive protein and 17% higher interleukin-6 levels - **Health Implications**: Both markers are strong predictors of cardiovascular disease - **Mechanism**: Trans fats influence atherogenesis (plaque formation) and increase visceral adipose tissue - **Visceral Fat Issue**: This abdominal fat itself leaks inflammatory cytokines, creating a continuous inflammatory cycle ### Practical Advice: Avoid hydrogenated oils completely. Choose whole food snacks and beverages without artificial trans fats. ## 3. Alcohol ### Key Points: - **Two-Pronged Approach**: Affects inflammation through direct biochemical pathways and gut health damage - **Gender Differences**: - Women: Alcohol intake linearly associated with higher uric acid levels - Men: Alcohol intake linearly associated with higher C-reactive protein levels - **Gut Health Impact**: Alcohol damages epithelial cells in the intestinal tract, leading to "leaky gut" - **Lipopolysaccharides (LPS)**: When gut lining is damaged, these bacterial components leak into bloodstream, triggering inflammatory cascade - **Core Mechanism**: LPS are foreign particles that shouldn't be in bloodstream, causing fundamental inflammatory response ### Practical Advice: Limit alcohol consumption to a couple of days per week to minimize inflammatory impact. ## 4. Processed Meats ### Key Points: - **Clarification**: The issue is processing, not red meat itself - **Study Evidence**: - Analysis of over 1 million people across 20 studies - Processed meat consumers had 42% higher risk of cardiovascular disease and 19% increased risk of type 2 diabetes - Red meat itself was not found to be a significant driver - **Mechanism**: Advanced Glycation End Products (AGEs) formed when reduced sugars interact with proteins - **AGE Effects**: - Can accumulate in arteries and trap plaque - Reduce nitric oxide synthesis, decreasing vessel wall flexibility - Make vessels more rigid, contributing to cardiovascular issues ### Practical Advice: Choose fresh, unadulterated lean meats over processed options like bologna, sausages, or deli meats. ## 5. Sodium Benzoate (in combination with sugar) ### Key Points: - **Context**: Found primarily in sodas and processed beverages as preservative - **Double Impact**: Combines with sugar's inflammatory effects for compounded negative impact - **Study Evidence**: - Rodent studies showed dose-dependent inflammatory responses at 200mg/kg and above - Increased tumor necrosis factor-alpha, interleukin-6, and interleukin-1 beta - **Neurological Effects**: - 200mg/kg dosage in mice showed decreased maze completion ability - Possible link to brain inflammation and anxiety-related behavioral changes - **Chemistry**: Created by combining benzoic acid with sodium hydroxide ### Practical Advice: Avoid sugary soft drinks that contain both high sugar content and sodium benzoate preservatives. ## Supporting Factors ### Gut Health Connection: - Diverse microbiome produces short-chain fatty acids that support glucose metabolism - Probiotics can help with insulin resistance and reduce inflammatory responses - Lipopolysaccharides from gut bacteria can trigger inflammation when they leak into bloodstream ## Conclusion Chronic inflammation represents a significant health risk that can damage cells, affect DNA, and contribute to serious conditions like cardiovascular disease and diabetes. While individual responses to foods vary due to bio-individuality, five categories consistently drive inflammation across populations: sugar and refined carbohydrates, trans fats, alcohol, processed meats, and sodium benzoate (especially in sugary beverages). The evidence shows that these foods work through various mechanisms—from direct biochemical pathways to gut health disruption—to create inflammatory responses that can become chronic and damaging over time. The key is not to develop orthorexic behaviors but to pay attention to how your body responds and make informed choices about limiting these inflammatory triggers. By understanding these mechanisms and making conscious dietary choices, individuals can significantly reduce their inflammatory burden and improve their overall health outcomes. The focus should be on whole, minimally processed foods while avoiding the combination of multiple inflammatory triggers, such as sugar and sodium benzoate in sodas.

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@OrganicallyOsborne 2025-09-24

Avocado helped me along my 110 pound weight loss journey, they assist in processing carbs!

12 2 replies
@Gizmo-g7h 2025-09-24

Thanks Thomas, great video! I love the tweaks you are making. A point I would add to this list is for heavens sake if you are doing all 5 of these in conjunction you are risking your life!! And many people are, without realizing the danger. Thomas, the videos you create are a public service that should be recognized.

6
@oohwha 2025-09-25

I skipped the 1st four as I've been avoiding them all for 25 years... but I didn't know much about Sodium Benzoate so that bit is very interesting! Liked the video and leaving this comment to help with the algorithms! (and hopefully keep your channel running without a need for all the A.I. BOTS!!!)

2
@Mike_Thompson 2025-10-31

That new microphone makes you sound crazy different.

0
@BobJ357 2025-09-25

Thanks Thomas!

0
@shanazsingh9661 2025-09-25

Thank you for the contents

0
@GatorNinetyNine 2025-09-25

Ty ty ty

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