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Lizard Venom Regrows 'Irreplaceable' Cartilage

2026-04-27 People & Blogs
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Dr Brad Stanfield
Dr Brad Stanfield
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🩺 Get your personalized health plan: https://drstanfield.com πŸ’Š Supplements I Take: https://drstanfield.com/pages/my-supplements πŸ’ŠMicroVitamin+ (Pro) Powder: https://drstanfield.com/products/microvitamin-plus πŸ’ŠMicroVitamin Standard Capsules: https://drstanfield.com/products/microvitamin βœ”οΈ X: https://x.com/BradStanfieldMD βœ”οΈ Patreon: https://www.patreon.com/bradstanfieldmd Here are the links to the research papers referenced in the video: Exenatide history (Eng's mail-order venom) β€” https://peptideinitiative.com/peptide-chronicles/exenatide Gila monster feeding pattern β€” https://www.zmescience.com/ecology/animals-ecology/gila-monster-ozempic-origin/ Raufman NIH "fishing expedition" β€” https://whyy.org/segments/ozempic-how-gila-monster-venom-led-to-weight-loss-drugs/ Exenatide / Wikipedia (Yalow training, exendin-4 isolation, VA patent refusal, 3 years rejection, Holst quote, Amylin licensing) β€” https://en.wikipedia.org/wiki/Exenatide Exendin-4 53% similarity to GLP-1 β€” https://pubmed.ncbi.nlm.nih.gov/15866711/ Native GLP-1 short half-life β€” https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1431292/full VA "veteran-specific ailment" β€” https://www.diabetesincontrol.com/dr-john-engs-research-found-that-the-saliva-of-the-gila-monster-contains-a-hormone-that-treats-diabetes-better-than-any-other-medicine/ Byetta FDA approval / dosing β€” https://investor.lilly.com/news-releases/news-release-details/amylin-and-lilly-announce-fda-approval-byettatm-exenatide Exenatide modest weight loss β€” https://pmc.ncbi.nlm.nih.gov/articles/PMC3241299/ Liraglutide / Victoza approval β€” https://www.nejm.org/doi/full/10.1056/NEJMp1001578 Ozempic FDA approval β€” https://www.prnewswire.com/news-releases/novo-nordisk-receives-fda-approval-of-ozempic-semaglutide-injection-for-the-treatment-of-adults-with-type-2-diabetes-300567052.html Semaglutide 14.9% weight loss β€” https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 Wegovy obesity approval (2021) β€” https://www.prnewswire.com/news-releases/novo-nordisk-receives-fda-approval-for-wegovy-to-treat-adults-with-obesity-based-on-unprecedented-efficacy-for-a-prescription-medicine-in-clinical-trials-301306246.html SELECT cardiovascular trial β€” https://www.nejm.org/doi/full/10.1056/NEJMoa2307563 Harvard Gazette (Josephine Li & Nils Kruger quotes) β€” https://news.harvard.edu/gazette/story/2026/02/whats-next-for-glp-1s/ GLP-1 substance use disorders β€” https://www.bmj.com/content/392/bmj-2025-086886 Hardaway "less rewarding" quote β€” https://www.uab.edu/news/research-innovation/the-glp-1-revolution-what-uab-researchers-are-discovering-about-how-these-drugs-work FLOW kidney trial β€” https://www.nejm.org/doi/full/10.1056/NEJMoa2403347 GLP-1R wide tissue distribution β€” https://pmc.ncbi.nlm.nih.gov/articles/PMC9455625/ Hunter 1743 cartilage declaration β€” https://royalsocietypublishing.org/rstl/article/42/470/514/25806/VI-Of-the-structure-and-diseases-of-articu-lating Cartilage limited self-repair β€” https://pmc.ncbi.nlm.nih.gov/articles/PMC10071204/ Cartilage repair unmet needs β€” https://www.mdpi.com/1648-9144/61/1/24 595 million OA prevalence β€” https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(23)00163-7/fulltext Knee replacement cost ($19,568 US) β€” https://pmc.ncbi.nlm.nih.gov/articles/PMC10368258/ Karin Payne "no cure" quote β€” https://news.cuanschutz.edu/medicine/arthritis-glp-1-agonists-obese-patient Weight loss β†’ 4x knee-joint load reduction β€” https://pubmed.ncbi.nlm.nih.gov/15986358/ STEP 9 trial (semaglutide + knee OA) β€” https://www.nejm.org/doi/abs/10.1056/NEJMoa2403664 Qin et al. β€” pair-fed mouse design, mechanism, human pilot, 17% cartilage increase, WOMAC, authors' caution β€” https://www.cell.com/cell-metabolism/fulltext/S1550-4131(26)00008-2 Di Chen "independent of weight loss" quote β€” https://news.cgtn.com/news/2026-02-12/-Weight-loss-wonder-drug-can-also-treats-osteoarthritis-study-finds-1KHcUiXzHsQ/p.html Thumbnail by James Kelly Video edited by Troy Young Script by John Milliken The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel.

Top Comments (10)

@patricialee76 2026-04-27

I knew my stack was missing something. Not getting enough lizard bites.

168 3 replies
@bcninety8210 2026-04-27

Lizards regrow their tails. Maybe this is why.

83 11 replies
@ueb4631 2026-04-28

Snake oil salesmen might have been onto something but lizard venom is where it's at.

68 9 replies
@skinnymoonbob 2026-04-27

put it in the MicroVitamin :)

66 2 replies
@89PrinceLucifer 2026-04-27

MOM! I need VENOM!

41
@chazsroczynski5666 2026-04-27

Haha. As a veteran, I found the slight mistake at 2:29 saying a "veterinarian specific ailment" hilarious. In all fairness, sometimes I think horses are treated better than vets πŸ˜…. Comment in good fun. Content is great πŸ‘.

36 1 replies
@heyRex 2026-04-27

This has potential to dramatically improve healthspan while aging. Jogging at 70.

24 5 replies
@jamesfortune243 2026-04-29

I guess we should call it a healer monster. πŸ™‚

14
@g-man2507 2026-04-29

This is amazing … who would have imagined that such an astonishing breakthrough would arrive via lizard 🦎 venom?

4
@DrBradStanfield 2026-04-27

🩺 Get your personalized health plan: https://drstanfield.com πŸ’ŠMicroVitamin (multivitamin & mineral that I take): https://drstanfield.com/products/microvitamin

3 1 replies

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