Did One Tiny Tweak Just Solve Heart Disease?

🩺 Get your personalized health plan: https://drstanfield.com 💊 Supplements I Take: https://drstanfield.com/pages/my-supplements 💊MicroVitamin+ (Pro) Powder: https://drstanfield.com/products/microvitamin-plus 💊MicroVitamin Standard Capsules: https://drstanfield.com/products/microvitamin ✔️ X: https://x.com/BradStanfieldMD ✔️ Patreon: https://www.patreon.com/bradstanfieldmd Here are the links to the research papers referenced in the video: Verve-102 adverse events https://www.cgtlive.com/view/verve-moves-on-second-gen-cardiovascular-crispr-therapy-verve-102-adverse-events Framingham Heart Study — about https://www.framinghamheartstudy.org/fhs-about/ Optimal LDL 50–70 mg/dL https://pubmed.ncbi.nlm.nih.gov/15172426/ LDL causes ASCVD (EAS consensus) https://academic.oup.com/eurheartj/article/38/32/2459/3745109 Broken PCSK9 protects against CHD https://www.nejm.org/doi/full/10.1056/NEJMoa054013 Lower LDL extends lifespan (MR) https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.14811 CRISPR-Cas9 discovery history https://pmc.ncbi.nlm.nih.gov/articles/PMC9377665/ CRISPR acquired resistance (2007) https://embryo.asu.edu/pages/crispr-acquired-resistance-against-viruses-2007 CRISPR is bacterial immunity https://www.science.org/doi/10.1126/science.1138140 Programmable Cas9 DNA cleavage https://www.science.org/doi/10.1126/science.1225829 2020 Nobel Chemistry for CRISPR https://pmc.ncbi.nlm.nih.gov/articles/PMC7782372/ CRISPR causes large deletions https://pmc.ncbi.nlm.nih.gov/articles/PMC6390938/ SCID-X1 gene therapy leukemia https://www.jci.org/articles/view/35700 David Liu — Broad bio https://www.broadinstitute.org/bios/david-liu David Liu profile — Harvard Magazine https://www.harvardmagazine.com/science/david-liu-harvard-gene-editing-research-disease-cures VERVE-102 Heart-2 trial (NEJM) https://www.nejm.org/doi/full/10.1056/NEJMoa2601283 Intellia MAGNITUDE clinical hold https://ir.intelliatx.com/news-releases/news-release-details/intellia-therapeutics-provides-update-magnitude-clinical-trials Intellia nex-z patient death https://www.cgtlive.com/view/patient-treated-trial-intellia-transthyretin-amyloidosis-gene-editing-therapy-nex-z-dies Liu Breakthrough Prize / Tapley — Harvard Gazette https://news.harvard.edu/gazette/story/2025/04/rewriting-genetic-destiny-gene-base-editing/ Base-edited CAR7 T-cells in T-ALL (NEJM) https://www.nejm.org/doi/full/10.1056/NEJMoa2505478 PCSK9 base editing in primates (Nature) https://www.nature.com/articles/s41586-021-03534-y Lilly VERVE-102 results https://investor.lilly.com/news-releases/news-release-details/single-dose-lillys-pcsk9-base-editor-verve-102-reduced-pcsk9-88 Thumbnail by James Kelly Video edited by Troy Young Script by John Milliken The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel.