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Control Your Vagus Nerve to Improve Mood, Alertness & Neuroplasticity

2025-06-23 Science & Technology
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Andrew Huberman
Andrew Huberman
7.5m subscribers

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Description

In this episode I explain how your vagus nerve—an extensive neural pathway linking your brain and body in both directions—powerfully regulates your mood, digestion, alertness and even certain food cravings, and I explain how you can activate certain vagus nerve pathways to improve your heart rate variability (HRV), a key marker of health and longevity. I also explain how to control vagal pathways to enhance your focus and alertness to improve learning and neuroplasticity. And I explain how your vagus nerve controls levels of serotonin in both your gut and brain, impacting your mood and emotional resilience and how to keep that pathway robust. Episode show notes: https://go.hubermanlab.com/K36mJhe *Thank you to our sponsors* AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Joovv: https://joovv.com/huberman ROKA: https://roka.com/huberman Function: https://functionhealth.com/huberman *Follow Huberman Lab* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Timestamps* 00:00:00 Vagus Nerve 00:02:43 Sponsors: LMNT & Joovv 00:05:41 Cranial Nerves, Inputs (Afferents) & Outputs (Efferents), Sensory & Motor 00:12:40 Vagus Nerve & Sensory Pathways, Body & Brain 00:18:30 Sensory Information, Chemical & Mechanical Information 00:23:49 Sympathetic & Parasympathetic Nervous Systems, Vagus Nerve, Tool: Calming & Auricular (Ear) Sensation 00:30:19 Sponsors: AG1 & ROKA 00:33:38 Vagus Nerve Motor Outputs 00:36:00 Autoregulation, Improving Heart Rate Variability (HRV) Tools: HR Deceleration 00:49:46 Aging, Declining HRV, Health, Activity, Tool 00:52:31 Tool: Exercise, Increase Alertness for Cognitive & Physical Activity, Motivation 01:04:26 Sponsor: Function 01:06:14 Adult Neuroplasticity & Learning, Acetylcholine, Alpha GPC Nicotine 01:11:48 Tools: High-Intensity Exercise, Increase Alertness, Focus & Learning; Sleep 01:18:14 Serotonin, Gut, Brain & Mood, Depression & SSRIs 01:21:34 Serotonin, Improve Mood & Gut Health, Irritable Bowel Syndrome (IBS), Tools: Low-Sugar Fermented Foods, Tryptophan 01:28:49 Mood, Depression, Gut Health & Vagal Signaling, Probiotics 01:32:12 Calming Down via Vagus Nerve, Tool: Neck Peri-Arterial Vagus Stretch 01:42:00 Tools: Calming Down, Humming, Extended Exhales 01:46:38 Recap 01:48:46 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

Top Comments (10)

@Aseel-l7m 2025-06-23

I just came here to say it's 300 episodes Over the course of 5 years of hard work and tireless effort by Dr. Andrew, Huberman, and his team.

1.1k 31 replies
@AndreSilva-lt5eg 2025-06-29

To anyone who's suffering depression, anxiety, insomnia and other mental health problems, you are not alone. I feel you. You are so brave. You are doing so well. I'm proud of you. I'm sending you a virtual hug ❤ For me, it wasn’t therapy or meds that helped the most — it was reconnecting with myself. I started using the exercises in Shift Your Mind by Alexander Brooks, and it made me feel human again. The anxiety that used to control my whole day barely shows up now! 🙏❤

469 14 replies
@foodculturevlog 2025-06-25

We are blessed to be this age of earth where we have Youtube & Dr Huberman

291 3 replies
@Jessybytes 2025-06-23

If calmness had a playlist, your voice would be track one. Thanks for giving the vagus nerve the attention it deserves and for making neuroscience strangely addictive

212 2 replies
@spacetu 2025-06-23

Actions 1. Do a “physiological sigh” — take two deep inhales through your nose (one long, one short), then a long exhale through your mouth. This activates calming pathways in the vagus nerve, helping you quickly reduce anxiety and stress. 2. Practice slow, extended exhales several times a day - This strengthens your vagus nerve’s ability to regulate heart rate and stress, improving heart rate variability (HRV), a marker of resilience and longevity. 3. Do light leg or core movement (e.g., a short walk or a few squats) when you feel sluggish - This stimulates the vagus nerve via adrenaline release, increasing brain alertness and motivation to move. 4. Gently massage behind your ears or inside your outer ear with your fingers - Activates a minor branch of the vagus nerve that can promote a subtle calming effect. Generated by SpaceTu. Link in Bio.

207 3 replies
@danherrickphilosophy 2025-07-17

The buried lead here is the extraordinary amount of courage and self-restraint it took Dr. Huberman not to subtitle this episode "What Happens in Vagus." we are all grateful.

166 9 replies
@PGproductionsHD 2025-06-23

After 168 days of waiting, the solo episode drought is finally over! Thank you for the insights, Dr. Huberman — and you’re welcome for my unwavering interest in science.

152
@m_c_d 2025-06-23

Yoga teacher here....Kundalini Yoga. I was given extensive education about the vagus nerve during year long training in 2013. Its brilliant to see this topic being cover in a more "mainstream" context.

112 9 replies
@dnastyness5811 2025-06-23

Man I miss the solo episodes, they are awesome

83 3 replies
@jodydulceak4171 2025-11-13

I went to thr ER because I was laying down and my heart suddenly started pounding out of my chest so fast that I couldn't even count the beats from my pulse. Once the doc came in, he had me do a vagal maneuver i believe called the reverse valsalva maneuver which lowered my heart rate. He had me do it one more time and said "Okay, good that got you down to 140." I said "DOWN to 140??? What was it at before?!" 240 BPM. That visit I was diagnosed with Supraventricular tachycardia originating in the AV node. That's when I became fascinated with the vagus nerve and started doing my own research. This episode included some things I hadn't learned yet and was fun to listen to. Thank you!!

30 1 replies

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