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Scientists Compared Butter vs Seed Oil Head-to-Head (the results surprised me)

2025-09-24 People & Blogs
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Thomas DeLauer
Thomas DeLauer
4.0m subscribers

Navigating Saturated Fat vs. Seed Oil Evidence: Short-Term Gains vs. Long-Term Oxidation Risk

Review the latest research comparing butter and seed oils to clarify short-term biomarker improvements versus long-term risks related to fat oxidation. Determine how individual metabolic health and caloric status dictate the optimal fat consumption strategy.

Short Summary

  • Short-term studies often show polyunsaturated fats (PUFAs) improve liver health markers like liver fat accumulation and inflammation.
  • Consuming excess saturated fat, particularly when overfed, significantly increases liver triglycerides through fat mobilization, not just direct synthesis.
  • Long-term risk appears linked to the high accumulation of linoleic acid in human fat tissue, which predisposes LDL particles to oxidation.
  • Metabolic context is crucial: activity levels dictate whether saturated fat intake contributes positively (via energy use) or negatively (via organ deposition).

This discussion moves beyond nutritional dogma, examining trials that pit butter against vegetable oils. We analyze why PUFAs rapidly improve liver health in some contexts, but also explore the underlying evidence suggesting that high consumption of specific PUFAs like linoleic acid creates long-term risks via oxidation pathways. Understanding these competing factors helps tailor fat intake to your individual metabolic state.

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Description

Use Code THOMAS25 for 25% off Your First Order of SEED: https://www.seed.com/thomasyt This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Click HERE to Subscribe: https://www.youtube.com/c/ThomasDeLauerOfficial?sub_confirmation=1 Please check out the new Shorts channel, DeLauer Clips and Workouts, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://link.springer.com/article/10.1007/s00125-001-0768-3 https://www.sciencedirect.com/science/article/pii/S000291652302782X?via%3Dihub#f2 https://www.sciencedirect.com/science/article/pii/S216183132300114X https://www.bmj.com/content/bmj/346/bmj.e8707.full.pdf https://openheart.bmj.com/content/5/2/e000898 https://pubmed.ncbi.nlm.nih.gov/29844096/ https://www.nature.com/articles/s41430-023-01358-9 https://pmc.ncbi.nlm.nih.gov/articles/PMC11022414/ Timestamps ⏱ 0:00 - Intro 1:00 - 25% off Your First Order of SEED 1:53 - Butter vs Seed Oil Study 3:25 - Short-Term Effects of Reducing Saturated Fats 4:35 - Side Effects of Too Much Saturated Fat 5:57 - The Fatty Acid Composition of Our Body Fat Has Changed 7:30 - Oxidation | Oxidized LDL & Oxidized Oils 10:27 - Saturated Fat vs Unsaturated Fat vs Sugar Study 13:08 - Could Saturated Fat Be Beneficial For You? 14:32 - The Takeaway

Top Comments (10)

@james7751 2025-09-24

i always use butter for cookin' eggs...

22 2 replies
@mickwolf1077 2025-09-24

I never use veg oil, the oil doesn't come from veggies like the name implies. Butter is awesome.

15 3 replies
@See6H12O6 2025-09-24

Good one, it's grass fed butter overall that's better for you, but NOT when you are OVERFED, i.e., consuming an additional 1000 calories over your normal base caloric intake AND on a SAD diet.

13 7 replies
@albrackets8446 2025-09-24

Seed oils are usually always a marker for shitty foods.

9 5 replies
@ritsukohairsalon 2025-09-24

Ok, that was confusing. I didn't understand the words he said.

5
@JerryCorreia76 2025-09-24

One of the best explanations between saturated fats and seed oils that I have heard so far.

1
@gustavomiranda7584 2025-09-24

Thanks Thomas!!

1
@gregrucc6176 2025-10-29

Thank you Thomas

0
@monnoo8221 2025-09-24

very good, important info. And even the start was nice :))

0
@bryanbrossart4435 2025-09-24

Excellent!! Ty

0

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