Navigate Select ESC Close

450mg Wipes Out Insulin Resistance (and Fatty Liver)

2026-04-01 People & Blogs
26.7k
1.3k
96
Thomas DeLauer
Thomas DeLauer
4.0m subscribers

Unlock all features

FREE: Get instant access to 10 AI summaries, chats, or transcripts per day.

Description

Go to http://rhonutrition.com, use code DELAUER20, and get 20% off! This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like this that we are able to provide the content that we do for free. Click HERE to Subscribe: https://www.youtube.com/c/ThomasDeLauerOfficial?sub_confirmation=1 Please check out the new Shorts channel, DeLauer Clips and Workouts, here: https://www.youtube.com/channel/UCQPQImPsw74KhO0Zy2-leyA/videos Please Subscribe to my Email Newsletter Here: https://www.thomasdelauer.com/life-optimization-tactics/ Follow More of My Daily Life on Instagram: http://www.Instagram.com/ThomasDeLauer References https://pmc.ncbi.nlm.nih.gov/articles/PMC10075255/ https://www.sciencedirect.com/science/article/pii/S2211124721005945 https://pmc.ncbi.nlm.nih.gov/articles/PMC12718416/ https://journals.sagepub.com/doi/10.1089/jmf.2017.4080? https://www.gastrojournal.org/article/S0016-5085(02)15967-1/fulltext Timestamps ⏱ 0:00 - Intro 1:41 - Glutathione & NAFLD 6:24 - 20% off Rho Nutrition 7:38 - Ferroptosis 11:32 - How to Increase Glutathione Levels 15:31 - 4 Dietary Levers 17:57 - Things that Deplete Glutathione 19:48 - How to Reduce Cortisol Over Age 40

Top Comments (10)

@Behealthier-hc 2026-04-01

No one is talking about how Tylenol depletes glutathione levels. Probably lots of different pharmaceuticals do too.

61 7 replies
@Natepositivity 2026-04-01

Glycine 10mg and NAc 1g combine with excersise

48 3 replies
@christopherf7423 2026-04-02

That study you mentioned at 13:09 is insane. We give one group what we think is good stuff. And we give the other group poison: maltodextrin. And surprise, the maltodextrin group did poorly. We are talking about dropping fat from a fatty liver, and they gave them maltodextrin which spikes insulin and blood sugar faster than table sugar. This of course, causes fatty liver.

19 1 replies
@FTW_Trade 2026-04-01

AI Summary: This video, presented by Thomas DeLauer, explores the critical role of glutathione in liver health, insulin resistance, and cellular longevity. It highlights how glutathione depletion is not just a symptom of fatty liver disease, but a driving factor. ### Key Takeaways: The Power of Glutathione: As the body's primary antioxidant (made of glutamate, cysteine, and glycine), it protects against oxidative stress. When mitochondrial glutathione levels drop, it leads to impaired energy production and heightened inflammation (1:41-3:35). Ferroptosis: The video introduces this iron-dependent form of cell death, where cells essentially 'rust' and burst due to lipid peroxidation. Glutathione, via the GPX (glutathione peroxidase) enzyme, is the primary defense against this process (7:38-10:02). Dietary and Lifestyle Levers: To improve glutathione levels, you should focus on precursors and supporting cellular pathways: Precursors: Incorporate whey protein, NAC (N-acetylcysteine), and glycine-rich foods like bone broth (5:28-6:05, 12:01-13:40). NRF2 Activation: Eat cruciferous vegetables (broccoli sprouts, kale, cabbage) and garlic to signal the body to produce more glutathione (14:48-15:45). Support Pathways: Ensure adequate selenium for GPX function, and maintain NADPH levels (via Vitamin C and carbohydrates) to help recycle used glutathione (10:48-11:00, 16:41-17:35). Factors That Deplete Glutathione: Alcohol, excessive seed oils, sleep deprivation, and environmental toxins can rapidly exhaust your stores. Prioritizing quality sleep is crucial because that is when glutathione recycling is restored (17:57-19:28). Supplementation: While the body needs its own natural production, liposomal glutathione is recommended for its high bioavailability compared to standard oral capsules, especially during periods of high stress or toxic exposure (6:12-7:10, 19:28-19:46).

17 1 replies
@GygaxGirl 2026-04-02

Be aware that if you have MTHFR gene mutations with COMT issues, these recommendations may not work for you.

14
@Andy.Harris 2026-04-01

Oh I just noticed. Grats on 4 mil subs

13
@gogogo1064 2026-04-02

Coffee ground enemas. Every sunday after church 💪💪

6 2 replies
@chesnadailey3411 2026-04-02

Brazil nuts usually have high amounts of mold. Get your selenium somewhere else.

1
@cameron6554 2026-04-02

Thanks for the info and video. 👍

1
@mahuaghosh7155 2026-04-02

Every logic behind these biomolecule uptake are real . Thank you for explainable it with biochemistry .

0

Unlock the Data Inside
Turn Videos into Knowledge

  • Get FREE 10/day: transcripts, summaries, chats
  • Chat with videos, export text & PDF
  • $1 free API credit for RAG, chatbots & research

Free forever plan • All features unlocked

App screenshot