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The Anti-Aging Supplement Scam (New Evidence)

2026-04-07 People & Blogs
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Dr Brad Stanfield
Dr Brad Stanfield
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For weekly health research summaries and extra insights, sign up here 👉 https://drstanfield.com/pages/sign-up 💊 Supplements I Take: https://drstanfield.com/pages/my-supplements 💊MicroVitamin+ (Pro) Powder: https://drstanfield.com/products/microvitamin-plus 💊MicroVitamin Standard Capsules: https://drstanfield.com/products/microvitamin 🩺 Get your personalized health roadmap (free): https://drstanfield.com/pages/roadmap Timestamps: 00:00 The Interventions Testing Program 03:41 The Breakthrough: Rapamycin 05:21 The Excitement Around Astaxanthin and AKG 09:44 The ITP's Latest Results 11:16 Conclusion and Key Takeaways ✔️ X: https://x.com/BradStanfieldMD ✔️ Patreon: https://www.patreon.com/bradstanfieldmd Here are the links to the research papers referenced in the video: Astaxanthin/meclizine ITP 2023 — https://link.springer.com/article/10.1007/s11357-023-01011-0 Rejuvant "longevity escape velocity" press release — https://www.globenewswire.com/news-release/2023/03/28/2635803/0/en/67-Year-Old-Founder-of-Ponce-De-Leon-Health-Achieves-Longevity-Escape-Velocity-with-Rejuvant.html ITP 2026 paper (all 11 compounds fail) — https://link.springer.com/article/10.1007/s11357-026-02201-2 NIA ITP overview — https://www.nia.nih.gov/research/dab/interventions-testing-program-itp NIA ITP about page (UM-HET3 mice) — https://www.nia.nih.gov/research/dab/interventions-testing-program-itp/about-itp NR extends lifespan in mice (Zhang 2016) — https://www.science.org/doi/10.1126/science.aaf2693 NR fails ITP (17-a-estradiol paper) — https://pmc.ncbi.nlm.nih.gov/articles/PMC8135004/ Rapamycin discovery (Easter Island) — https://pmc.ncbi.nlm.nih.gov/articles/PMC9494524/ Rapamycin extends lifespan (Harrison 2009, Nature) — https://www.nature.com/articles/nature08221 Science top 10 breakthroughs 2009 — https://www.science.org/doi/10.1126/science.326.5960.1600 ITP supported interventions list — https://www.nia.nih.gov/research/dab/interventions-testing-program-itp/supported-interventions AKG extends lifespan (Buck Institute 2020) — https://pmc.ncbi.nlm.nih.gov/articles/PMC8508957/ Lithgow quote (Buck press release) — https://www.buckinstitute.org/news/a-metabolite-produced-by-the-body-increases-lifespan-and-dramatically-compresses-late-life-morbidity-in-mice/ Sinclair AKG tweet — https://x.com/davidasinclair/status/1300868036023459841 Rejuvant "8 year" study (Demidenko 2021) — https://www.aging-us.com/article/203736/text Horvath clock comparison — https://www.mdpi.com/2673-8856/5/2/28 Resveratrol in mice (Sinclair 2006, Nature) — https://www.nature.com/articles/nature05354 GSK acquires Sirtris for $720M — https://www.fiercebiotech.com/biotech/glaxosmithkline-gsk-to-acquire-sirtris-pharmaceuticals-a-world-leader-sirtuin-research-and Resveratrol not a direct SIRT1 activator — https://pmc.ncbi.nlm.nih.gov/articles/PMC2832984 SRT501 trial halted (kidney damage) — https://www.fiercebiotech.com/biotech/safety-concerns-force-glaxo-to-suspend-enrollment-srt501-trial GSK shuts down Sirtris — https://www.bioworld.com/articles/438084 Kaeberlein "most debunked" quote — https://www.levels.com/blog/matt-kaeberlein-longevity-science Astaxanthin skin meta-analysis — https://pmc.ncbi.nlm.nih.gov/articles/PMC8472736/ Thumbnail by James Kelly Video edited by Troy Young Script by John Milliken The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel.

Top Comments (10)

@OurFamilyInMotion 2026-04-07

Again, not helping with longevity doesn't mean it doesn't help with other parts of health.

190 30 replies
@cordyone 2026-04-07

Astaxanthin stops my skin from burning in the sun, and thats good enough for me.

132 20 replies
@olegoginskiy4043 2026-04-07

We’re expecting a video soon: “I Was Completely Wrong About AKG and Astaxanthin.”

109 5 replies
@hoffmancapote 2026-04-07

I do take astaxanthin but not for longevity, just for its anti-oxidant effect I have noticed my eyesight has improved and my optician agreed with me that it has. Another thing, it is not expensive.

84 7 replies
@rgilbar 2026-04-07

I’m an optometrist (retired)and I use astaxanthin 12-24mg/day for dry eyes and discovered it also j helps big-time with night vision. My son (also an optometrist) has had dozens of patients report much improved dry-eye symptoms. Longevity? Let you know in 20 years (I’m 74).

54 2 replies
@Adel3625 2026-04-07

If a compound reduces frailty by 40% but doesn't extend life by a single day, is it a failure? For those of us in our 60s, quality of function (mitochondrial health, recovery) is the metric that matters now. The ITP is a great 'Binary Audit' (Live/Die), but it misses the 'Performance Optimization' that researchers are targeting.

41 2 replies
@Cyndy-w1f 2026-04-07

Astaxanthin took away my daily post stroke headaches. I’ve suffered with these for 25 years so I am ecstatic,

27
@Vincent-fv1ch 2026-04-07

It's the year 2026 and scientists can still not conduct proper studies with placebo groups..

24 1 replies
@DrBradStanfield 2026-04-07

All 23 studies referenced in the video are linked in the video's description 💊Supplements that Dr Brad takes: https://drstanfield.com/pages/my-supplements 💊MicroVitamin (multivitamin & mineral that I take): https://drstanfield.com/products/microvitamin 🩺 Get your personalized health roadmap from Dr Brad: https://drstanfield.com/pages/roadmap

10
@coder8515 2026-04-08

Just because something doesn’t increase lifespan (which is also hard to prove) doesn’t mean it can’t improve quality of life.

10

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