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This Supplement Has 0.2% Absorption — and It Still Works

2026-03-18 People & Blogs
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Dr Brad Stanfield
Dr Brad Stanfield
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Description

For weekly health research summaries and extra insights, sign up here 👉 https://drstanfield.com/pages/sign-up 💊 Supplements I Take: https://drstanfield.com/pages/my-supplements 💊MicroVitamin+ (Pro) Powder: https://drstanfield.com/products/microvitamin-plus 💊MicroVitamin Standard Capsules: https://drstanfield.com/products/microvitamin 🩺 Get your personalized health roadmap (free): https://drstanfield.com/pages/roadmap Timestamps: 00:00 Hyaluronic Acid Problems 00:52 Studies on Hyaluronic Acid and Skin Health 02:46 Understanding Absorption of Hyaluronic Acid 05:14 New Findings on Absorption 07:00 New Clinical Trial on Hyaluronic Acid 08:44 Possible Mechanisms of Action 00:09:46 Key Takeaways ✔️ X: https://x.com/BradStanfieldMD ✔️ Patreon: https://www.patreon.com/bradstanfieldmd Here are the links to the research papers referenced in the video: https://www.sciencedirect.com/science/article/abs/pii/S0144861723003454?via%3Dihub Molecular weight and gut microbiota determine the bioavailability of orally administered hyaluronic acid https://www.nature.com/articles/s41598-025-32758-5 Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522662/ Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period https://pmc.ncbi.nlm.nih.gov/articles/PMC4110621/ Ingested hyaluronan moisturizes dry skin https://pubmed.ncbi.nlm.nih.gov/34933842/ Oral intake of a new full-spectrum hyaluronan improves skin profilometry and ageing: a randomized, double-blind, placebo-controlled clinical trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661223/ Oral administration of hyaluronic acid to improve skin conditions via a randomized double-blind clinical test, 2023 https://pmc.ncbi.nlm.nih.gov/articles/PMC10082573/ The Effectiveness of Injectable Hyaluronic Acid in the Improvement of the Facial Skin Quality: A Systematic Review https://pubs.acs.org/doi/10.1021/jf8017029 Absorption, Uptake and Tissue Affinity of High-Molecular-Weight Hyaluronan after Oral Administration in Rats and Dogs https://pmc.ncbi.nlm.nih.gov/articles/PMC3512263/ Oral Administration of Polymer Hyaluronic Acid Alleviates Symptoms of Knee Osteoarthritis: A Double-Blind, Placebo-Controlled Study over a 12-Month Period Thumbnail by James Kelly Video edited by Troy Young Script by John Milliken The links above are affiliate links, so I receive a small commission every time you use them to purchase a product. The content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel.

Top Comments (10)

@dannil666 2026-03-19

Pls cover methylene blue next!🌀

8 1 replies
@lenorelopez748 2026-03-18

Are you referring to wrinkles in a younger person or someone over 70? does it matter how old you are and how long you’ve had the wrinkles? Thank you so much.

8
@patusoro4781 2026-03-23

At the 10:00 minute mark, you'll realize this is a commercial.

6
@Schu2505 2026-03-19

I find it interesting that Glucosamine plays a foundational role in the production of hyaluronic acid (HA), acting as one of the primary "building blocks" your body uses to construct the molecule, but folks running glucosamine trials were surprised because it appeared to extend lifespan (probably not realizing the connection). I wonder how much supplementation with it increases HA production.

5
@jjjames6894 2026-03-19

I'm in my 40s & spend lots of time in texas sun throughout year & been on HLA for a few years along with a portfolio/body building diet & my skin has improved looking at detailed pics from a few years ago, I use zinc oxide & castor oil/petroleum on face & microneedle .9mm & take 12g astaxanthin/day but poor sleep bc newborn, so who knows how much the HLA is helping but something is going against the odds considering I like to stay tan. Thank u Dr s for an update on HLA!🙌

4 1 replies
@DrBradStanfield 2026-03-18

All 9 studies referenced in the video are linked in the video's description 💊Supplements that Dr Brad takes: https://drstanfield.com/pages/my-supplements 💊MicroVitamin (multivitamin & mineral that I take): https://drstanfield.com/products/microvitamin 🩺 Get your personalized health roadmap from Dr Brad: https://drstanfield.com/pages/roadmap

3
@rigilchrist 2026-03-22

Can you comment on the topical application of the liquid form of the acid?

1
@ninjashinobi2413 2026-03-19

I use a hyaluronic acid hand wash as a shower gel to help smooth my skin, though I significantly dilute it since it makes my skin very shiny (seriously)...

1
@Manu329is 2026-03-27

perfect, mine ist 2 to 5 kDa - will stick to it

0
@tajmeal 2026-03-21

@06:46 It is very easy to have doubts... excellent.

0

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